Comparison of the survival outcomes between retrocolic and antecolic Roux‐en‐Y reconstruction after gastrectomy for gastric cancer

• Published in: Annals of gastroenterological surgery 2024-05, Vol.8 (3), p.443-449
• Main Authors: Honda, Michitaka, Ri, Motonari, Kinoshita, Takahiro, Kawakubo, Hirofumi, Aizawa, Masaki, Bamba, Takeo, Matsuda, Satoru, Kawamura, Hidetaka, Yoshida, Mitsumasa, Nunobe, Souya
• Format: Article
• Language: English
• Subjects: antecolic route; Cancer therapies; Chemotherapy; Cohort analysis; Colon; Comparative studies; Gastric cancer; Gastrointestinal surgery; Hospitals; Intestinal obstruction; Laparoscopy; Nutritional status; Patients; retrocolic route; Roux‐en‐Y reconstruction; Small intestine; Surgeons; Surgical anastomosis; Surgical outcomes
• ISSN: 2475-0328; 2475-0328
• DOI: 10.1002/ags3.12779

Background There are two methods of Roux‐en‐Y (RY) reconstruction after gastrectomy: the antecolic route (ACR) and retrocolic route (RCR). There is no evidence to support that the ACR achieves comparable long‐term survival. Methods This was a multi‐center historical cohort study. Patients diagnosed with clinical T3/4a and any N stage who underwent open gastrectomy and R0 resection for gastric adenocarcinoma between January 2006 and December 2012 were enrolled. The primary outcome was the hazard ratio of ACR for overall survival, with adjustment for confounding factors by propensity score matching, and a Cox proportional hazards model. Results A total of 1758 eligible patients were identified from the database. After matching, 410 patients in the ACR and RCR groups were included in the final analysis. The adjusted hazard ratio (95% CI) for ACR was 1.148 (0.870–1.492). The five‐year survival rates in the ACR and RCR groups were 74.3% (69.5–78.4) and 77.3% (72.3–81.2), respectively. The short‐term surgical outcomes of the two groups did not differ to a statistically significant extent. Conclusion The route used to lift the jejunum in RY reconstruction did not affect the incidence of long‐term survival or postoperative complications. The ACR and RCR are both acceptable options for RY reconstruction during gastric cancer surgery. The route used to lift the jejunum in Roux‐en‐Y reconstruction after gastrectomy does not affect the long‐term survival. The ACR and RCR are both suitable options for RY reconstruction during gastric cancer surgery.