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Association between obstructive sleep apnea and hyperuricemia/gout in the general population: a cross-sectional study

Obstructive sleep apnea (OSA) is linked to various health conditions, including cardiovascular diseases and metabolic disorders. Hyperuricemia and gout may be associated with OSA, but large-scale studies on this are limited. This study aimed to investigate the association between hyperuricemia/gout...

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Bibliographic Details
Published in:BMC musculoskeletal disorders 2025-01, Vol.26 (1), p.14-9, Article 14
Main Authors: Park, Suyeon, Bak, Seong-Hyeok, Kim, Hyun-Sook, Lee, Kyung-Ann
Format: Article
Language:English
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Summary:Obstructive sleep apnea (OSA) is linked to various health conditions, including cardiovascular diseases and metabolic disorders. Hyperuricemia and gout may be associated with OSA, but large-scale studies on this are limited. This study aimed to investigate the association between hyperuricemia/gout and OSA using data from the Korea National Health and Nutrition Survey (KNHANES). Using the 2019-2021 KNHANES data, 11,728 participants were selected. OSA risk was assessed using the STOP-BANG questionnaire score, which is as follows: (1) high-risk (5-8), (2) intermediate-risk (3-4), and (3) low-risk (0-2). Anthropometric, socioeconomic, health-related variables, and biochemical measurements, including serum uric acid (SUA) levels, were included in the analysis. Multiple regression analyses examined the association between the STOP-BANG score and hyperuricemia/gout. After assigning weights, among 25,354,276 individuals, 3,114,119 (12.2%) had a high OSA risk. The high OSA risk group exhibited higher SUA levels (5.9 mg/dL) than those of the intermediate (5.6 mg/dL) and low OSA risk groups (4.7 mg/dL) (P 
ISSN:1471-2474
1471-2474
DOI:10.1186/s12891-024-08264-6