Anterior Skull Base Glomangioma-Induced Osteomalacia

Abstract Oncogenic osteomalacia (OO) is an uncommon but treatable cause of osteomalacia related to tumor production of FGF23, usually caused by benign mesenchymal neoplasms. Paranasal sinus glomangiomas are a rare cause of OO, with only one previously reported case. Here we describe a second case (f...

Full description

Saved in:
Bibliographic Details
Published in:Journal of neurological surgery reports 2017-01, Vol.78 (1), p.e9-e11
Main Authors: Gresham, Malia S., Shen, Steven, Zhang, Yi J., Gallagher, Kelly
Format: Article
Language:English
Subjects:
Case Report
glomangioma
glomus tumor
oncogenic osteomalacia
paranasal sinus tumor
Citations: Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Abstract Oncogenic osteomalacia (OO) is an uncommon but treatable cause of osteomalacia related to tumor production of FGF23, usually caused by benign mesenchymal neoplasms. Paranasal sinus glomangiomas are a rare cause of OO, with only one previously reported case. Here we describe a second case (first reported in English) of paranasal sinus glomangioma-induced osteomalacia in a 42-year-old man. He presented with weakness and multiple spontaneous fractures, and was found to have an ethmoid sinus glomangioma with intracranial extension. The tumor was removed via endoscopic endonasal approach to the anterior skull base, which resulted in complete resolution of symptoms and no further evidence of disease 1 year postoperatively.
ISSN:2193-6358
2193-6366
DOI:10.1055/s-0036-1597599