Toxic epidermal necrolysis

Objective: To recognize the common ocular signs and symptoms of toxic epidermal necrolysis (TEN), differentiate it from similar diseases, give the appropriate management, and provide continuity of care. Methods: This is a case report of a 21-year-old female patient admitted for ocular involvement of...

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Bibliographic Details
Published in:Philippine journal of ophthalmology 2011-06, Vol.36 (1), p.42-45
Main Authors: Rosalie Mae M. Reyes, MD, Jacinto Dy Liacco, MD
Format: Article
Language:English
Subjects:
adverse drug reaction
scalded-skin syndrome
toxic epidermal necrolysis
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Summary:Objective: To recognize the common ocular signs and symptoms of toxic epidermal necrolysis (TEN), differentiate it from similar diseases, give the appropriate management, and provide continuity of care. Methods: This is a case report of a 21-year-old female patient admitted for ocular involvement of TEN secondary to an acute food reaction and an adverse drug reaction to intravenous cloxacillin. Results: The patient had hyperemic conjunctivae with infiltration, mucopurulent discharge, and pseudomembrane formation with a corneal epithelial defect. The ocular symptoms were treated with copious irrigation of the conjunctival sac, daily membrane peeling, topical antibiotics, and topical steroids. The patient was advised regular follow-up to prevent symblepharon formation. Conclusion: With the appropriate diagnosis and management of TEN, ocular symptoms may be relieved and complications prevented.
ISSN:0031-7659