Readmission Rate, Predictors, Outcomes, and Burden of Readmission of Hepatorenal Syndrome in the United States: A Nationwide Analysis

ABSTRACT Background Nationwide US data on readmission rates for patients with cirrhosis admitted with hepatorenal syndrome (HRS) is lacking. We reviewed 30‐day readmission rates after HRS‐related hospitalizations, the associated predictors of readmissions, and their impact on resource utilization an...

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Bibliographic Details
Published in:JGH open 2024-11, Vol.8 (11), p.e70062-n/a
Main Authors: Sohail, Abdullah, Chaudhary, Ammad J., Bhinder, Muhammad Mujtaba, Zahid, Khadija, Brown, Kyle
Format: Article
Language:English
Subjects:
Ascites
Chronic obstructive pulmonary disease
Comorbidity
Costs
Demographics
Health care policy
hepatorenal syndrome
Hospitalization
Hospitals
Hypertension
inpatient mortality
Kidney diseases
Length of stay
Liver cirrhosis
Liver diseases
Medicaid
Medicare
Mortality
Original
Patients
Postal codes
predictors of readmission
readmission rate
resource utilization
Statistical analysis
Survival analysis
Variables
Citations: Items that this one cites
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Summary:ABSTRACT Background Nationwide US data on readmission rates for patients with cirrhosis admitted with hepatorenal syndrome (HRS) is lacking. We reviewed 30‐day readmission rates after HRS‐related hospitalizations, the associated predictors of readmissions, and their impact on resource utilization and mortality in the United States. Methods We identified all adults admitted with HRS between 2016 and 2019 using the Nationwide Readmission database of the Agency for Healthcare Research and Quality's Healthcare Cost and Utilization Project. The primary outcome was all‐cause 30‐day readmission rate. Secondary outcomes were inpatient mortality rate, predictors of readmission, and resource utilization. Results We identified 245 850 hospitalizations of patients admitted for HRS in the United States from 2016 to 2019. Of these, 214 890 met the inclusion criteria. Mean age was 59.16 years, and 61.31% were males. Medicare was the most common primary payer (44.82%) followed by Medicaid (25.58%). The readmission rate was 24.6% within 30 days of discharge from index hospitalization. The most common cause of readmission was alcoholic cirrhosis with ascites (14.87%), followed by sepsis (9.32%) and unspecified hepatic failure (9%). The in‐hospital mortality rate for index hospitalization was 29.52% and 14.35% among those readmitted within 30 days. The mean length of stay (12.33 days vs. 7.15 days, p 
ISSN:2397-9070
2397-9070
DOI:10.1002/jgh3.70062