Hematological parameters and early-onset coronary artery disease: a retrospective case–control study based on 3366 participants

Background: Thrombosis and inflammation are crucial elements in the pathogenesis of cardiovascular disease. Hematological parameters elucidate information involving the inflammatory and blood coagulation processes. Objectives: The current study explored the association of hematological parameters wi...

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Bibliographic Details
Published in:Therapeutic advances in chronic disease 2023-01, Vol.14, p.20406223221142670
Main Authors: Wang, Huan, Li, Hui, Wang, Yan, Zhao, Cong, Tian, Qing-Wu, Wang, Qing, He, Guo-Wei, Lun, Li-Min, Xuan, Chao
Format: Article
Language:English
Subjects:
Blood
Cardiovascular disease
Chronic illnesses
Coronary vessels
Hematology
Hemoglobin
Original Research
Vein & artery diseases
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Summary:Background: Thrombosis and inflammation are crucial elements in the pathogenesis of cardiovascular disease. Hematological parameters elucidate information involving the inflammatory and blood coagulation processes. Objectives: The current study explored the association of hematological parameters with EOCAD to identify specific risk factors. Design: A single-center retrospective case–control study was conducted with 1693 coronary artery disease patients and 1693 controls. Methods: Hematological parameters were examined through an automated analyzer. Results: The basophil percentage was significantly reduced in EOCAD (0.43 ± 0.26, p 
ISSN:2040-6223
2040-6231
DOI:10.1177/20406223221142670