Characteristics of the gut microbiota in pregnant women with fetal growth restriction

Fetal growth restriction (FGR) in utero leads to failure of fetus to reach the genetically normal growth potential. Currently available means of treating FGR are limited. And it remains unknown how pregnant women who give birth to FGR fetus differ in gut microbiota composition from normal pregnant w...

Full description

Saved in:
Bibliographic Details
Published in:BMC pregnancy and childbirth 2022-04, Vol.22 (1), p.297-297, Article 297
Main Authors: Tu, Xinzhi, Duan, Chun, Lin, Bingying, Li, Kangfeng, Gao, Jie, Yan, Huaying, Wang, Kejian, Zhao, Zhao
Format: Article
Language:English
Subjects:
16S rDNA sequencing
Bar codes
Birth weight
Case-Control Studies
Cesarean section
Diabetes
Discriminant analysis
Feces
Female
Fetal growth restriction (FGR)
Fetal Growth Retardation
Fetus
Gastrointestinal Microbiome
Gestational age
Glucose
Glycometabolism
Gut microbiota
Humans
Insulin resistance
Metabolism
Microbiota
Obesity
Pregnancy
Pregnant Women
Probiotics
Thermal cycling
Umbilical cord
Womens health
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Fetal growth restriction (FGR) in utero leads to failure of fetus to reach the genetically normal growth potential. Currently available means of treating FGR are limited. And it remains unknown how pregnant women who give birth to FGR fetus differ in gut microbiota composition from normal pregnant women. In this case-control study, fecal samples were obtained from maternal rectum in the operation room by an obstetrician under strict aseptic conditions. We compared gut microbiota of 14 pregnant women with FGR and 18 normal controls by performing 16S rDNA amplicon sequencing. We identified significant differences in β-diversity between the FGR and control groups (P 
ISSN:1471-2393
1471-2393
DOI:10.1186/s12884-022-04635-w