Characteristics of Patients with Surgical Closure of an Atrial Septal Defect during Infancy

Background: Surgical closure of an atrial septal defect (ASD) is infrequently indicated during infancy. We evaluated the clinical characteristics and outcomes of patients who underwent surgical ASD closure during infancy. Methods: A single-center retrospective review was performed for 39 patients (1...

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Bibliographic Details
Published in:Journal of chest surgery 2023-05, Vol.56 (3), p.155-161
Main Authors: Yoo, Byeong A, Kwon, Su Jin, Im, Yu-Mi, Kim, Dong-Hee, Choi, Eun Seok, Kwon, Bo Sang, Park, Chun Soo, Yun, Tae-Jin
Format: Article
Language:English
Subjects:
atrial heart septal defects
bronchopulmonary dysplasia
Clinical Research
congenital heart defects
infancy
pediatric cardiology
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Summary:Background: Surgical closure of an atrial septal defect (ASD) is infrequently indicated during infancy. We evaluated the clinical characteristics and outcomes of patients who underwent surgical ASD closure during infancy. Methods: A single-center retrospective review was performed for 39 patients (19 males) who underwent surgical ASD closure during infancy between 1993 and 2020. The median body weight percentile at the time of operation was 9.3. Results: During a median follow-up of 60.9 months, 4 late deaths occurred due to chronic respiratory failure. A preoperative history of bronchopulmonary dysplasia (BPD) was the only risk factor for late mortality identified in Cox regression (hazard ratio, 3.54; 95% confidence interval [CI], 1.75–163.04; p=0.015). The 5-year survival rate was significantly lower in patients with preoperative history of BPD (97.0% vs. 50.0%, p
ISSN:2765-1606
2765-1614
DOI:10.5090/jcs.22.133