Traffic noise exposure increases gastric acid secretion in rat

Noise is considered as one of the most severe sources of environmental and work place constraints. Noise effects on immune function, hormonal levels, cardiovascular and respiratory systems are well known. The aim of the study is to evaluate the effects of traffic noise on basal and stimulated gastri...

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Bibliographic Details
Published in:Acta medica Iranica 2010-03, Vol.48 (2), p.77-82
Main Authors: Moslehi, Azam, Nabavizadeh-Rafsanjani, Fatemeh, Keshavarz, Mansoor, Rouhbakhsh, Nematollah, Sotudeh, Masoud, Salimi, Ehsan
Format: Article
Language:English
Subjects:
Adaptation, Physiological
Analysis of Variance
Animals
gastric acid
Gastric Acid - secretion
Gastric Mucosa - pathology
Gastric Mucosa - secretion
inbred strains
Male
Noise
Noise, Transportation
Pentagastrin - pharmacology
Rats
Rats, Wistar
transportation
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Summary:Noise is considered as one of the most severe sources of environmental and work place constraints. Noise effects on immune function, hormonal levels, cardiovascular and respiratory systems are well known. The aim of the study is to evaluate the effects of traffic noise on basal and stimulated gastric acid secretion. 48 healthy rats were divided into five traffic noise exposures (1, 7, 14, 21, 28 days) and a control groups. Pentagastrin was used i.p. for stimulation of gastric acid secretion. The gastric contents were collected by the wash-out technique and then titrated. Histological studies were performed on gastric epithelial layer. In the 1, 7, 14 and 21 days traffic noise exposure, basal and pentagastrin-stimulated gastric acid secretion increased compared to the control group (P
ISSN:0044-6025
1735-9694