Calculated and measured radiation dose for the low energy xoft axxent eBT X-ray source

• Published in: BMC research notes 2023-02, Vol.16 (1), p.25-25, Article 25
• Main Authors: Can, Sümeyra, Atilla, Özge, Karaçetin, Didem
• Format: Article
• Language: English
• Subjects: Analysis; Balloons; Brachytherapy; Brain cancer; Breast cancer; Calibration; Dose measurements; Dosimetry; Drug dosages; Film Dosimetry; Intraoperative radiotherapy; Measurement; Patient outcomes; Photons; Radiation Dosage; Radiation dose; Radiation dosimetry; Radiation measurement; Radiation therapy; Radiography; Radioisotope brachytherapy; Research Note; Saline Solution; Scanners; Sodium Chloride; Tumors; Water; X-Rays; Xoft Axxent eBT
• ISSN: 1756-0500; 1756-0500
• DOI: 10.1186/s13104-023-06287-1

In this study, it was aimed to evaluate the functionality to deliver different prescription dose except 20 Gy for the Xoft Axxent Ebt (electronic Brachytherapy) system and analyzing the system in terms of radiation dosimetry in water and 0.9% isotonic Sodium Chloride (NaCl) solution. In the Xoft Axxent eBT, different prescription dose in single fraction were calculated for different balloon applicator volumes based on source position and irradiation times. EBT-XD Gafchromic film was calibrated at 6MV photon energy. A balloon applicator filled with 0.9% isotonic NaCl solution was used to deliver a radiation dose of 20 Gy, 16 Gy, 10 Gy on the applicator surface. Then the balloon applicator was filled with water and the same measurements were repeated. Finally, the balloon applicator was irradiated by positioning it at different distances in the water phantom to simulate the isodose contour. At the time the balloon applicator was filled with water and 0,9% NaCl solution, the difference between the planned dose and the absorbed dose was ~ 2% vs. 15% for 30 cc, ~ 5% vs. 14% for 35 cc and ~ 3,5% vs. 10% for 40 cc respectively. Finally, the absorbed dose at a distance of 1 cm from the applicator surface was measured as 9.63 Gy. In this study, it was showed that different prescription dose could be possible to deliver in the Xoft Axxent eBT system based on the standard plan. In addition, the absorbed dose was higher than the planned dose depending on the effective atomic number of NaCl solution comparing to water due to photoelectric effect in low energy photons. By measuring the dose distributions at different distances from the balloon applicator surface, the absorbed dose in tissue equivalent medium was determined and the isodose contours characteristics was simulated.