Ranolazine treatment for refractory angina in a patient with Hutchinson-Gilford progeria syndrome and end stage aortic stenosis

Management of symptoms in patients with inoperable aortic stenosis is often hard in clinical practice. We report a case of a patient with Hutchinson-Gilford progeria syndrome and end-stage aortic stenosis, considered not suitable for surgical or percutaneous approach, to whom the administration of r...

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Bibliographic Details
Published in:Cardiogenetics 2020-01, Vol.9 (1)
Main Authors: Limongelli, Giuseppe, Monda, Emanuele, Capozzi, Giovanbattista, Caiazza, Martina, Russo, Maria Giovanna
Format: Article
Language:English
Subjects:
aortic stenosis
Hutchinson-Gilford progeria syndrome
ranolazine
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Summary:Management of symptoms in patients with inoperable aortic stenosis is often hard in clinical practice. We report a case of a patient with Hutchinson-Gilford progeria syndrome and end-stage aortic stenosis, considered not suitable for surgical or percutaneous approach, to whom the administration of ranolazine resulted in a considerable improvement of angina, refractory to other treatments.
ISSN:2035-8253
2035-8148
DOI:10.4081/cardiogenetics.2019.8609