The outcome of surgery for congenital heart disease in India: A systematic review and metanalysis

The mortality risks of children undergoing various cardiac surgeries for congenital heart disease (CHD) in India are not well defined. We conducted a systematic review and meta-analysis to estimate the inhospital mortality of various common CHD surgeries reported in India and compared it to represen...

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Bibliographic Details
Published in:Annals of pediatric cardiology 2024-05, Vol.17 (3), p.164-179
Main Authors: Kadiyani, Lamk, Kalaivani, Mani, Iyer, Krishna S, Ramakrishnan, Sivasubramanian
Format: Article
Language:English
Subjects:
Analysis
Cardiac patients
Cardiovascular disease
Children
Congenital diseases
Congenital heart disease
congenital heart surgery
Genetic disorders
Health aspects
Heart diseases
low- and middle-income countries
Mortality
Online databases
operative mortality
Original
Pediatric cardiology
pooled mortality risk
Surgery
Surgical outcomes
Systematic review
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Summary:The mortality risks of children undergoing various cardiac surgeries for congenital heart disease (CHD) in India are not well defined. We conducted a systematic review and meta-analysis to estimate the inhospital mortality of various common CHD surgeries reported in India and compared it to representative data from established Western databases. We searched four bibliographic databases for studies published in India over the last 25 years. In total, 135 studies met the inclusion criteria and included 30,587 patients aged from 1 day to 65 years. The pooled mortality rate of 43 Indian studies reporting multiple CHD surgical outcomes is 5.63% (95% confidence interval [CI]: 4.26-7.16; = 93.9%), whereas the Western data showed a pooled mortality rate of 2.65% ( value for comparison
ISSN:0974-2069
0974-5149
DOI:10.4103/apc.apc_71_24