Reflectance Confocal Microscopy and Electrical Impedance Spectroscopy in the Early Detection of Melanoma in Changing Lesions during Long-term Follow-up of Very High-risk Patients

Electrical impedance spectroscopy has clinical relevance in diagnosing malignancy in melanocytic lesions. Sixty-eight lesions with changes during digital follow-up of patients at very high risk of developing melanoma were prospectively included in this study from February to December 2016. Electrica...

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Bibliographic Details
Published in:Acta dermato-venereologica 2022-07, Vol.102, p.adv00751-adv00751
Main Authors: Chavez-Bourgeois, Marion, Ribero, Simone, Barreiro, Alicia, Espinoza, Natalia, Carrera, Cristina, Garcia, Adriana, Alos, Llucia, Puig, Susana, Malvehy, Josep
Format: Article
Language:English
Subjects:
dermoscopy
Electrical Impedance Spectroscopy
melanoma
Original
reflectance confocal microscopy
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Summary:Electrical impedance spectroscopy has clinical relevance in diagnosing malignancy in melanocytic lesions. Sixty-eight lesions with changes during digital follow-up of patients at very high risk of developing melanoma were prospectively included in this study from February to December 2016. Electrical impedance spectroscopy and reflectance confocal microscopy were performed to evaluate their performance in this subset of difficult lesions. Forty-six lesions were considered suspicious on reflectance confocal microscopy and were excised, of these, 19 were diagnosed as melanoma. Fifteen melanomas were detected by electrical impedance spectroscopy, while 4 received a score lower than 4, which suggested no malignancy. The addition of reflectance confocal microscopy improves accuracy while maintaining the same sensitivity. In the case of electrical impedance spectroscopy scores
ISSN:0001-5555
1651-2057
DOI:10.2340/actadv.v102.1105