Clinicopathological findings and imaging features of intraductal papillary neoplasms in bile ducts

Intraductal papillary mucinous neoplasm of the bile duct (IPMN-B) is considered an uncommon tumor, and there is limited understanding of IPMN-B. This study aimed to investigate the prognosis and influential factors of the IPMN-B from 58 cases. The clinical data of 58 patients with pathologically con...

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Published in:PeerJ (San Francisco, CA) CA), 2020-09, Vol.8, p.e10040-e10040, Article e10040
Main Authors: Zhang, Honghui, Zhong, Zhendong, Kong, Gaoyin, Khan, Junaid, Zou, Lianhong, Jiang, Yu, Liu, Xiehong, Tang, Yixun, Jiang, Bo, Peng, Chuang, Song, Yinghui, Liu, Sulai
Format: Article
Language:English
Subjects:
Abdomen
Benign
Bile
Bile ducts
Biliary tract cancer
Biomarkers
Cancer metastasis
Carcinoembryonic antigen
Evidence Based Medicine
Fistula
Hospitals
Hyperplasia
Information management
Liver
Lymph nodes
Lymphatic system
Magnetic resonance imaging
Medical prognosis
Metastases
Metastasis
Multivariate analysis
Oncology
Papillary mucinous tumor in the bile duct
Patients
Prognosis
Radical resection
Risk factor
Risk factors
Surgery
Survival
Survival analysis
Tumor markers
Tumors
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Summary:Intraductal papillary mucinous neoplasm of the bile duct (IPMN-B) is considered an uncommon tumor, and there is limited understanding of IPMN-B. This study aimed to investigate the prognosis and influential factors of the IPMN-B from 58 cases. The clinical data of 58 patients with pathologically confirmed IPMN-B admitted to our hospital from January 1, 2012 to August 2017 were collected and analyzed. The patients were followed up by outpatient or telephone until January 1, 2019. SPSS 19.0 software was applied for data analysis. Survival analysis was performed using Kaplan-Meier method and parallel Log-rank test. Prognostic factors were analyzed by univariate analysis and multiple Cox regression model. Among of all the patients, 26 cases were benign tumors and 32 cases were malignant tumors. The preoperative tumor markers CA242 and CEA of malignant IPNM-B patients were significantly higher than those in benign tumors (  
ISSN:2167-8359
2167-8359
DOI:10.7717/peerj.10040