Seaweed Sulfated Polysaccharides against Respiratory Viral Infections

Respiratory viral infections have been a leading cause of morbidity and mortality worldwide. Despite massive advancements in the virology field, no specific treatment exists for most respiratory viral infections. Approved therapies against respiratory viruses rely almost exclusively on synthetic dru...

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Bibliographic Details
Published in:Pharmaceutics 2021-05, Vol.13 (5), p.733
Main Authors: Jabeen, Mehwish, Dutot, Mélody, Fagon, Roxane, Verrier, Bernard, Monge, Claire
Format: Article
Language:English
Subjects:
antiviral activity
approved antivirals
Bioengineering
Biomaterials
Chemical Sciences
Coronaviruses
COVID-19
Galenic pharmacology
Human health and pathology
Hépatology and Gastroenterology
Immunology
Immunotherapy
Infectious diseases
Life Sciences
mechanism of action
Medicinal Chemistry
Microbiology and Parasitology
Pharmaceutical sciences
Polymers
Pulmonology and respiratory tract
Respiratory diseases
respiratory virus
Review
seaweed
sulfated polysaccharide
Vaccinology
Viral infections
Virology
Viruses
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Summary:Respiratory viral infections have been a leading cause of morbidity and mortality worldwide. Despite massive advancements in the virology field, no specific treatment exists for most respiratory viral infections. Approved therapies against respiratory viruses rely almost exclusively on synthetic drugs that have potential side effects, restricting their use. This review aims to present natural marine sulfated polysaccharides possessing promising antiviral activity against respiratory viruses that could be a safe alternative to synthetic broad-spectrum antiviral drugs. The antiviral properties of marine sulfated polysaccharides are presented according to their mechanism of action on different types and strains of respiratory viruses, and the potential limits of their use are discussed.
ISSN:1999-4923
1999-4923
DOI:10.3390/pharmaceutics13050733