Cumulative Effects of Particulate Matter Pollution and Meteorological Variables on the Risk of Influenza-Like Illness

• Published in: Viruses 2021-03, Vol.13 (4), p.556
• Main Authors: Toczylowski, Kacper, Wietlicka-Piszcz, Magdalena, Grabowska, Magdalena, Sulik, Artur
• Format: Article
• Language: English
• Subjects: Adolescent; Adult; Aged; Air Pollutants - adverse effects; Air Pollutants - analysis; Air pollution; Air Pollution - adverse effects; Air temperature; Child; Child, Preschool; Cities; Coronaviruses; COVID-19; COVID-19 - epidemiology; COVID-19 - virology; Epidemiology; Female; Humans; Humidity; Illnesses; Influenza; influenza-like illness; Male; Meteorological Concepts; Middle Aged; Outdoor air quality; Particulate matter; Particulate Matter - adverse effects; Particulate Matter - analysis; Poland - epidemiology; Pollutants; Precipitation; Public health; Respiratory Tract Infections - epidemiology; Respiratory Tract Infections - etiology; SARS-CoV-2 - physiology; Severe acute respiratory syndrome coronavirus 2; Trends; Variables; Young Adult
• ISSN: 1999-4915; 1999-4915
• DOI: 10.3390/v13040556

The cold season is usually accompanied by an increased incidence of respiratory infections and increased air pollution from combustion sources. As we are facing growing numbers of COVID-19 cases caused by the novel SARS-CoV-2 coronavirus, an understanding of the impact of air pollutants and meteorological variables on the incidence of respiratory infections is crucial. The incidence of influenza-like illness (ILI) can be used as a close proxy for the circulation of influenza viruses. Recently, SARS-CoV-2 has also been detected in patients with ILI. Using distributed lag nonlinear models, we analyzed the association between ILI, meteorological variables and particulate matter concentration in Bialystok, Poland, from 2013-2019. We found an exponential relationship between cumulative PM pollution and the incidence of ILI, which remained significant after adjusting for air temperatures and a long-term trend. Pollution had the greatest effect during the same week, but the risk of ILI was increased for the four following weeks. The risk of ILI was also increased by low air temperatures, low absolute humidity, and high wind speed. Altogether, our results show that all measures implemented to decrease PM concentrations would be beneficial to reduce the transmission of SARS-CoV-2 and other respiratory infections.