Pyrethroid-treated bed nets impair blood feeding performance in insecticide resistant mosquitoes

The blood feeding performance of female mosquitoes directly impacts their ability to transmit malaria. Yet their host seeking and blood feeding behaviours in the presence of insecticide-treated nets (ITNs) are still poorly understood. This work explores how both insecticide resistant and susceptible...

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Bibliographic Details
Published in:Scientific reports 2023-06, Vol.13 (1), p.10055-10055, Article 10055
Main Authors: Barreaux, Priscille, Ranson, Hilary, Foster, Geraldine M., McCall, Philip J.
Format: Article
Language:English
Subjects:
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692/699/255/1629
Animals
Anopheles
Aquatic insects
Blood
Culicidae
Feeding behavior
Female
Humanities and Social Sciences
Humans
Ingestion
Insecticide Resistance
Insecticide-Treated Bednets
Insecticides
Insecticides - pharmacology
Malaria
Mosquito Control
Mosquitoes
multidisciplinary
Nets
Pyrethrins - pharmacology
Pyrethroids
Science
Science (multidisciplinary)
Vector-borne diseases
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Summary:The blood feeding performance of female mosquitoes directly impacts their ability to transmit malaria. Yet their host seeking and blood feeding behaviours in the presence of insecticide-treated nets (ITNs) are still poorly understood. This work explores how both insecticide resistant and susceptible Anopheles gambiae s.l. mosquitoes interact with pyrethroid nets (PermaNet 2.0 or Olyset net) or an untreated net (UTN) while attempting to blood feed on a human arm. Regardless of mosquito resistance status, the ITNs did not efficiently prevent host searching but reduced blood feeding success by 34.1 (29.31–38.95) %. The Permanet and Olyset net reduced to 227.5 (208.19–246.77) sec and 235.9 (214.03–257.74) sec the average blood feeding duration from 369.9 (342.78–397.04) sec with the UTN. The ingested blood volume was on average 22% lower for all mosquitoes exposed to insecticide. When feeding through ITNs, the blood volume flow rate of the susceptible strain increased by 35%, but no significant difference was found in the resistant strain. Thus, whilst the presence of the insecticide in ITNs reduced mosquito blood feeding success and blood volume, the mosquito’s ability to respond by accelerating her rate of blood ingestion may further reduce the impact of ITNs on resistant mosquitoes.
ISSN:2045-2322
2045-2322
DOI:10.1038/s41598-023-35958-z