COVID-19 associated pulmonary aspergillosis (CAPA) in a pregnant woman

Viral or bacterial co-infections with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have been reported in the literature. However, the knowledge on Aspergillus co-infection among patients with coronavirus disease 2019 (COVID-19) is limited. COVID‐19‐associated pulmonary aspergillosis...

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Bibliographic Details
Published in:Autopsy & case reports 2021, Vol.11, p.e2021313-e2021313
Main Authors: Agrawal, Shruti, Phulware, Ravi Hari
Format: Article
Language:English
Subjects:
ANATOMY & MORPHOLOGY
COVID-19
Fungi
PATHOLOGY
Pulmonary Aspergillosis
Respiratory Distress Syndrome
SARS-CoV-2
Short Communication
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Summary:Viral or bacterial co-infections with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have been reported in the literature. However, the knowledge on Aspergillus co-infection among patients with coronavirus disease 2019 (COVID-19) is limited. COVID‐19‐associated pulmonary aspergillosis (CAPA) has been seen in critically ill COVID-19 patients with acute respiratory distress syndrome (ARDS), which has raised concerns about the worsening disease course of COVID-19 and increasing mortality. We describe a clinical case of CAPA infection and acute respiratory distress syndrome (ARDS) with a deathly outcome in a previously well, non-immunocompromised pregnant woman with intrauterine death of the fetus. Hence, we suggest that clinicians and pathologists keep alerting the possible occurrence of pulmonary aspergillosis in severe/critical COVID-19 patients, and aggressive investigations should be done to rule out the possibility of CAPA so that early treatment can be administrated.
ISSN:2236-1960
2236-1960
DOI:10.4322/acr.2021.313