The association of metabolic syndrome components and chronic kidney disease in patients with hypertension

• Published in: Lipids in health and disease 2019-12, Vol.18 (1), p.229-229, Article 229
• Main Authors: Xie, Kun, Bao, Liwen, Jiang, Xiaofei, Ye, Zi, Bing, Jianping, Dong, Yugang, Gao, Danchen, Ji, Xiaoping, Jiang, Tingbo, Li, Jiehua, Li, Yan, Luo, Suxin, Mao, Wei, Peng, Daoquan, Qu, Peng, Song, Shangming, Wang, Hui, Wang, Zhaohui, Xu, Biao, Yin, Xinhua, Yu, Zaixin, Zhang, Xinjun, Zhang, Zixin, Zhu, Zhiming, Gao, Xiufang, Li, Yong
• Format: Article
• Language: English
• Subjects: Age; Analysis; Blood glucose; Blood pressure; Care and treatment; Chronic kidney disease; Chronic kidney failure; Cities and towns; Diabetes; Diabetes mellitus; Family medical history; Fasting; Glucose; Hypertension; Kidney diseases; Medical research; Metabolic syndrome; Risk factors; Studies; Triglyceride; Triglycerides; Womens health
• ISSN: 1476-511X; 1476-511X
• DOI: 10.1186/s12944-019-1121-5

Hypertension is a highly prevalent disease and the leading cause of chronic kidney disease (CKD). Metabolic syndrome could also be the risk factor for CKD. We sought to study the association between metabolic syndrome components and the prevalence of CKD in patients with hypertension. We carried out a multi-center cross-sectional study from Apr. 2017- Apr. 2018 in 15 cities in China. A total of 2484 patients with hypertension were enrolled. Among them, 56% were male and the average age was 65.12 ± 12.71 years. The systolic BP/diastolic BP was 142 ± 18/83 ± 12 mmHg. Metabolic syndrome components turned out to be highly prevalent in patients with hypertension, ranging from 40 to 58%. The prevalence of chronic kidney disease reached 22.0%. Multi-variate logistic analysis revealed that elevated triglyceride (TG) (OR = 1.81, 95% CI 1.28-2.57, p