Dosimetric effect of rotational setup errors in single-isocenter volumetric-modulated arc therapy of multiple brain metastases

Aim: The aim of this study is to investigate the dosimetric effects of rotational uncertainties in patient positioning on target coverage in stereotactic radiosurgery (SRS) of multiple brain metastases using single isocenter volumetric modulated arc therapy (VMAT). Materials and Methods: Ten SRS cas...

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Bibliographic Details
Published in:Journal of medical physics 2019-04, Vol.44 (2), p.84-90
Main Authors: Selvan, Kasirajan, Padma, Ganesan, Revathy, Murugesan, Nambi Raj, N, Senthilnathan, K, Babu, P
Format: Article
Language:English
Subjects:
Accuracy
Brain
Brain cancer
Cancer metastasis
Computer simulation
Metastasis
Original
Pitch (inclination)
Planning
Radiation therapy
Radiology
Radiosurgery
Radiotherapy
Rolling motion
Rotation
Rotational errors
stereotactic radiosurgery
Studies
Surgery
Therapy
Tumors
Uncertainty
volumetric modulated arc therapy
Yaw
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Summary:Aim: The aim of this study is to investigate the dosimetric effects of rotational uncertainties in patient positioning on target coverage in stereotactic radiosurgery (SRS) of multiple brain metastases using single isocenter volumetric modulated arc therapy (VMAT). Materials and Methods: Ten SRS cases with multiple brain metastases(2-8) planned with single isocenter non-coplanar VMAT technique were investigated in this study. Pitch, yaw and roll displacements of 1, 3 and 5° were simulated about isocenter along each axes and nine plans were obtained for each case. Gross tumor volume (GTV) coverage obtained on simulated plans were compared with the original plan on four metrics of mean dose (Dmean), minimum dose to GTV (Dmin), dose to 95% of GTV (D95) and the volume covered by the 95% of the prescribed dose (V95). Results: At 1° rotation about 4% of the PTV had V95 and D95 values
ISSN:0971-6203
1998-3913
DOI:10.4103/jmp.jmp_103_18