Multimodality imaging to identify lipid-rich coronary plaques and predict periprocedural myocardial injury: Association between near-infrared spectroscopy and coronary computed tomography angiography

This study compares the efficacy of coronary computed tomography angiography (CCTA) and near-infrared spectroscopy intravascular ultrasound (NIRS-IVUS) in patients with significant coronary stenosis for predicting periprocedural myocardial injury during percutaneous coronary intervention (PCI). We p...

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Bibliographic Details
Published in:Frontiers in cardiovascular medicine 2023-03, Vol.10, p.1127121-1127121
Main Authors: Ota, Hideaki, Matsuo, Hitoshi, Imai, Shunsuke, Nakashima, Yuki, Kawase, Yoshiaki, Okubo, Munenori, Takahashi, Hiroshi, Kawai, Hideki, Sobue, Yoshihiro, Kawasaki, Masanori, Kondo, Takeshi, Muramatsu, Takashi, Izawa, Hideo
Format: Article
Language:English
Subjects:
Cardiovascular Medicine
coronary computed tomography angiography
lipid-rich plaque
near-infrared spectroscopy
percutaneous coronary intervention
periprocedural myocardial injury (PMI)
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Summary:This study compares the efficacy of coronary computed tomography angiography (CCTA) and near-infrared spectroscopy intravascular ultrasound (NIRS-IVUS) in patients with significant coronary stenosis for predicting periprocedural myocardial injury during percutaneous coronary intervention (PCI). We prospectively enrolled 107 patients who underwent CCTA before PCI and performed NIRS-IVUS during PCI. Based on the maximal lipid core burden index for any 4-mm longitudinal segments (maxLCBI4mm) in the culprit lesion, we divided the patients into two groups: lipid-rich plaque (LRP) group (maxLCBI4mm ≥ 400;  = 48) and no-LRP group (maxLCBI4mm 
ISSN:2297-055X
2297-055X
DOI:10.3389/fcvm.2023.1127121