The Effect of Melatonin on Increasing the Health Related Quality of Life in Non-Metastatic Breast Cancer Patients: Three-Year Follow up a Clinical Trial

Introduction: Although breast cancer is common worldwide, if diagnosed early and treated on time, the probability of recovery is high and patients often experience a long life. Reducing the quality of life is a common side effect in patients. Melatonin may have an important role in fatigue, sleep di...

Full description

Saved in:
Bibliographic Details
Published in:Integrative cancer therapies 2024-01, Vol.23, p.15347354241237520-15347354241237520
Main Authors: Keshtpour Amlashi, Zahra, Sheida, Fateme, Anbiaee, Robab, Tapak, Leili, Hosseini, Seyed Rohallah, Mosaedian, Hossein, Barati, Nastaran
Format: Article
Language:English
Subjects:
Breast cancer
Breast Neoplasms - therapy
Clinical trials
Early experience
Female
Follow-Up Studies
Humans
Melatonin
Melatonin - therapeutic use
Metastases
Metastasis
Quality of Life
Sleep disorders
Surveys and Questionnaires
Citations: Items that this one cites
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Introduction: Although breast cancer is common worldwide, if diagnosed early and treated on time, the probability of recovery is high and patients often experience a long life. Reducing the quality of life is a common side effect in patients. Melatonin may have an important role in fatigue, sleep disorders and, as a result, the health-related quality of life (HRQoL) in people. About 184 patients with breast cancer were enrolled in 2 groups: intervention with daily melatonin intake of 18 mg for 3 years (93 patients) and the control group with placebo intake (91 patients). Health-related quality of life and the effect of melatonin on increasing that were evaluated with the EORTC QLQ-C30 questionnaire, third edition at the beginning, 2 months later and 3 years after the beginning of the study. Results: The general score of the HRQoL was significantly different both in the passage of time and in the comparative study of the 2 groups, and it was better in the melatonin group (P 
ISSN:1534-7354
1552-695X
DOI:10.1177/15347354241237520