The predictive value of the renal resistive index for contrast-induced nephropathy in patients with acute coronary syndrome

• Published in: BMC cardiovascular disorders 2019-02, Vol.19 (1), p.36-36, Article 36
• Main Authors: Xu, Zheng-Rong, Chen, Jun, Liu, Yuan-Hui, Liu, Yong, Tan, Ning
• Format: Article
• Language: English
• Subjects: Acute coronary syndrome; Acute Coronary Syndrome - diagnostic imaging; Acute Coronary Syndrome - physiopathology; Acute Coronary Syndrome - therapy; Acute coronary syndromes; Acute kidney failure; Adult; Aged; Biomarkers; Cardiac patients; Cardiology; Cardiovascular disease; Care and treatment; Chronic kidney failure; CIN; Clopidogrel; Contrast Media - adverse effects; Contrast-induced nephropathy; Coronary angiography; Coronary Angiography - adverse effects; Coronary heart disease; Creatinine; Doppler effect; Female; Hemodialysis; Hospitals; Humans; Hypertension; Hyperuricemia; Kidney - blood supply; Kidney diseases; Kidney Diseases - chemically induced; Kidney Diseases - diagnostic imaging; Kidney Diseases - physiopathology; Laboratories; Male; Medical research; Middle Aged; Nephropathy; Patients; Percutaneous Coronary Intervention - adverse effects; Predictive Value of Tests; Prospective Studies; Radiography, Interventional - adverse effects; Regression analysis; Renal Circulation; Renal resistive index; Risk Assessment; Risk Factors; RRI; Studies; Time Factors; Treatment Outcome; Ultrasonography, Doppler, Color; Ultrasound; Vascular Resistance
• ISSN: 1471-2261; 1471-2261
• DOI: 10.1186/s12872-019-1017-3

Percutaneous coronary intervention (PCI) has been associated with contrast-induced nephropathy (CIN) at a rate that varies depending on the patient's risk factors. This study was conducted to evaluate the predictive value of the renal resistive index (RRI) for CIN in patients with acute coronary syndrome (ACS) undergoing PCI. This prospective study enrolled 146 consecutive patients with ACS. Renal Doppler ultrasound examinations to measure RRI were performed pre-PCI and at 1 h and 24 h after PCI. The primary endpoint was CIN, defined as a relative (≥25%) or absolute (≥0.5 mg/dL; 44 μmol/L) increase in serum creatinine from baseline within 48 h after contrast exposure. CIN was identified in 31 patients (21.2%); however, none of the patients required haemodialysis. Compared to patients without CIN, higher RRIs were observed at 1 h (0.71 ± 0.05 vs. 0.65 ± 0.06, p