Comparison of Cardiac Repolarization After Transcatheter Aortic Valve Implantation and Surgical Aortic Valve Replacement: A Longitudinal Study

Introduction Transcatheter aortic valve implantation (TAVI) has been established as an alternative to surgical aortic valve replacement (SAVR) for high-risk patients. To assess the impact of TAVI on cardiac repolarization, we compared QT dispersion (QTD) and the interval from the peak to the end of...

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Bibliographic Details
Published in:Cardiology and Therapy 2020-06, Vol.9 (1), p.97-105
Main Authors: Chino, Satoru, Yamanaka, Eriko, Takasusuki, Toshifumi, Hamaguchi, Shinsuke, Yamaguchi, Shigeki
Format: Article
Language:English
Subjects:
Cardiac repolarization
Cardiology
Cardiovascular diseases
Care and treatment
Complications and side effects
Heart valve replacement
Internal Medicine
Medicine
Medicine & Public Health
Original Research
Patient outcomes
QT dispersion
Surgical aortic valve replacement
Tpeak–Tend
Transcatheter aortic valve implantation
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Summary:Introduction Transcatheter aortic valve implantation (TAVI) has been established as an alternative to surgical aortic valve replacement (SAVR) for high-risk patients. To assess the impact of TAVI on cardiac repolarization, we compared QT dispersion (QTD) and the interval from the peak to the end of the T wave (Tpeak–Tend: TpTe) between the patients who underwent TAVI and those who underwent SAVR and TpTe between the patients who underwent TAVI or SAVR. Methods This retrospective study was approved by the ethics committee of Dokkyo Medical University Hospital. The study included 45 patients who underwent TAVI and 45 patients who underwent SAVR. The QT, corrected QT (QTc), QTD, QTc dispersion (QTcD), Tp–Te, Tp–Te/QT, and Tp–Te/QTc were manually measured in standard 12-lead electrocardiogram (ECG) recordings obtained before surgery, immediately after surgery, 1 month, 3 months, and 6 months after surgery and compared between the two groups. Results No change was observed in RR, QT, QTc, Tp–Te, Tp–Te/QT, and Tp–Te/QTc in the two groups throughout the study. The QTD and QTcD significant decreased immediately after surgery in the TAVI group as compared to the SAVR group ( P  
ISSN:2193-8261
2193-6544
DOI:10.1007/s40119-019-00154-6