Sertraline-induced Hemichorea

BackgroundHemichorea-hemiballism is a syndrome secondary to different etiologies. Drug-induced hemichorea is a rare syndrome related to selective serotonin reuptake inhibitors. To the best of our knowledge, no previous cases of hemichorea associated with sertraline have been reported. Case ReportA 6...

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Bibliographic Details
Published in:Tremor and other hyperkinetic movements (New York, N.Y.) N.Y.), 2017-01, Vol.7, p.518-518
Main Authors: Gatto, Emilia M, Aldinio, Victoria, Parisi, Virginia, Persi, Gabriel, Da Prat, Gustavo, Bullrich, Maria Bres, Sanchez, Pilar, Rojas, Galeno
Format: Article
Language:English
Subjects:
Case Reports
Case study
Hemichorea
Hemichorea-hemiballism
Neurology
Sertraline
Sertraline-induced hemichorea
Tremor
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Summary:BackgroundHemichorea-hemiballism is a syndrome secondary to different etiologies. Drug-induced hemichorea is a rare syndrome related to selective serotonin reuptake inhibitors. To the best of our knowledge, no previous cases of hemichorea associated with sertraline have been reported. Case ReportA 65-year-old female noticed hemichorea 1 week after initiation of sertraline. After extensive investigations, other causes of hemichorea were excluded. Hemichorea remitted after sertraline withdrawal. DiscussionIn our patient, temporal association and the negative clinical assessment supported a diagnosis of likely drug-induced involuntary movement. We hypothesized that enhanced serotonergic transmission in the ventral tegmental area or nigrostriatum may be involved in sertraline-induced hemichorea.
ISSN:2160-8288
2160-8288
DOI:10.7916/D8XK999F