Sulfamethoxazole stone in a patient with extensive history of urolithiasis and recurrent urinary tract infections

Although rare, sulfamethoxazole-induced urolithiasis has been reported in patients taking trimethoprim-sulfamethoxazole (TMP/SMX). We present the case of a 79-year-old female who formed sulfamethoxazole stones in the setting of chronic indwelling catheterization with recurrent urinary tract infectio...

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Bibliographic Details
Published in:Urology case reports 2021-11, Vol.39, p.101812, Article 101812
Main Authors: Chase, Abbie M., Hines, Laena, Ellis, Elizabeth, Jain, Rajat, Quarrier, Scott O.
Format: Article
Language:English
Subjects:
Drug-induced
Endourology
Nephrolithiasis
Stones
Sulfamethoxazole-trimethoprim
Urinary tract infection
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Summary:Although rare, sulfamethoxazole-induced urolithiasis has been reported in patients taking trimethoprim-sulfamethoxazole (TMP/SMX). We present the case of a 79-year-old female who formed sulfamethoxazole stones in the setting of chronic indwelling catheterization with recurrent urinary tract infections (UTIs). The patient was a recurrent stone former with five prior stone composition analyses over a 10-year period varying from calcium phosphate to calcium oxalate, to struvite. We highlight the need for further investigation of this phenomenon given the frequent use of TMP/SMX in stone formers with recurrent infections.
ISSN:2214-4420
2214-4420
DOI:10.1016/j.eucr.2021.101812