Glucose biosensors: an overview of use in clinical practice

Blood glucose monitoring has been established as a valuable tool in the management of diabetes. Since maintaining normal blood glucose levels is recommended, a series of suitable glucose biosensors have been developed. During the last 50 years, glucose biosensor technology including point-of-care de...

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Bibliographic Details
Published in:Sensors (Basel, Switzerland) Switzerland), 2010-05, Vol.10 (5), p.4558-4576
Main Authors: Yoo, Eun-Hyung, Lee, Soo-Youn
Format: Article
Language:English
Subjects:
Biosensing Techniques - history
Biosensing Techniques - methods
Blood Glucose Self-Monitoring - instrumentation
Chemistry, Clinical - methods
diabetes mellitus
Glucose - analysis
glucose biosensor
History, 20th Century
Humans
Point-of-Care Systems
point-of-care testing
Review
self-monitoring of blood glucose
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Summary:Blood glucose monitoring has been established as a valuable tool in the management of diabetes. Since maintaining normal blood glucose levels is recommended, a series of suitable glucose biosensors have been developed. During the last 50 years, glucose biosensor technology including point-of-care devices, continuous glucose monitoring systems and noninvasive glucose monitoring systems has been significantly improved. However, there continues to be several challenges related to the achievement of accurate and reliable glucose monitoring. Further technical improvements in glucose biosensors, standardization of the analytical goals for their performance, and continuously assessing and training lay users are required. This article reviews the brief history, basic principles, analytical performance, and the present status of glucose biosensors in the clinical practice.
ISSN:1424-8220
1424-8220
DOI:10.3390/s100504558