A Case with Multiple Pathologies in the Pancreatic Head

Autoimmune pancreatitis (AIP) type 1, paraduodenal (groove) pancreatitis, and follicular pancreatitis are rare clinical entities whose diagnosis may be challenging, given the potential imaging overlap with pancreatic cancer. We performed a retrospective analysis of the medical chart of a patient wit...

Full description

Saved in:
Bibliographic Details
Published in:Biomedicines 2024-08, Vol.12 (8), p.1762
Main Authors: Vujasinovic, Miroslav, Ghazi, Sam, Kartalis, Nikolaos, Gustafsson Liljefors, Maria, D'Souza, Melroy A, Ghorbani, Poya, Löhr, J-Matthias
Format: Article
Language:English
Subjects:
Abdomen
Adenocarcinoma
autoimmune pancreatitis
Bile ducts
Biopsy
Cancer
Case Report
Comorbidity
Cysts
Diagnosis
Endoscopy
follicular pancreatitis
Immunoglobulin G
IPMN
Kidney stones
Kidneys
Lesions
Outpatient care facilities
Pancreas
Pancreatic cancer
pancreatic ductal adenocarcinoma
Pancreatitis
paraduodenal pancreatitis
Patients
Phosphatase
Small intestine
Veins & arteries
Citations: Items that this one cites
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
cited_by
cites cdi_FETCH-LOGICAL-c449t-83a92dec197fcf7f724e6352d587b723e78b39097282d4dc1f526741d0add4b43
container_end_page
container_issue 8
container_start_page 1762
container_title Biomedicines
container_volume 12
creator Vujasinovic, Miroslav
Ghazi, Sam
Kartalis, Nikolaos
Gustafsson Liljefors, Maria
D'Souza, Melroy A
Ghorbani, Poya
Löhr, J-Matthias
description Autoimmune pancreatitis (AIP) type 1, paraduodenal (groove) pancreatitis, and follicular pancreatitis are rare clinical entities whose diagnosis may be challenging, given the potential imaging overlap with pancreatic cancer. We performed a retrospective analysis of the medical chart of a patient with multiple pancreas pathologies. We present a case with multiple pancreas pathologies, including a poorly differentiated ductal adenocarcinoma of pancreatobiliary type, an intraductal papillary mucinous lesion (pre-existing lesion of IPMN type), and an inflammatory process with complex features, in which paraduodenal (groove) pancreatitis, follicular pancreatitis, and IgG4-related pancreatitis (AIP type 1) were also present. The diagnosis of AIP and paraduodenal pancreatitis is not always straightforward, and in some cases, it is not easy to differentiate them from pancreatic cancer. Surgery should be considered in patients when a suspicion of malignant/premalignant lesions cannot be excluded after a complete diagnostic work-up.
doi_str_mv 10.3390/biomedicines12081762
format article
fullrecord <record><control><sourceid>gale_doaj_</sourceid><recordid>TN_cdi_doaj_primary_oai_doaj_org_article_a136c0051e974c2db7bb3e019a0da0ff</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><galeid>A807425869</galeid><doaj_id>oai_doaj_org_article_a136c0051e974c2db7bb3e019a0da0ff</doaj_id><sourcerecordid>A807425869</sourcerecordid><originalsourceid>FETCH-LOGICAL-c449t-83a92dec197fcf7f724e6352d587b723e78b39097282d4dc1f526741d0add4b43</originalsourceid><addsrcrecordid>eNptklFvFCEQx4nR2Kb2GxiziS--XIWBXeDJXC5qm9Togz4TFoY7LnvLCbsav72cV2vPFB6YDP__D2YyhLxk9IpzTd_2Me3QRxdHLAyoYrKDJ-QcAORC01Y_fRCfkctStrQuzbhi4jk54xooBejOiVw2K1uw-RmnTfNpHqa4H7D5YqdNGtI6Ymni2EybQ2p0Ge0UXXON1r8gz4IdCl7enRfk24f3X1fXi9vPH29Wy9uFE0JPC8WtBo-OaRlckEGCwI634FslewkcpeprPVqCAi-8Y6GFTgrmqfVe9IJfkJsj1ye7Nfscdzb_MslG8yeR8trYXD81oLGMd47SlqGWwoHvZd9zpExb6i0NobLeHVn7ua_dczhO2Q4n0NObMW7MOv0wjPGWdS2vhDd3hJy-z1gms4vF4TDYEdNcDKdaMwFSQJW-_k-6TXMea68OKqkUoyD-qda2VhDHkOrD7gA1S0Urp1WdrqqrR1R1e9xFl0YMseZPDOJocDmVkjHcF8moOQyQeWyAqu3Vwwbdm_6OC_8N9_PBDQ</addsrcrecordid><sourcetype>Open Website</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>3097881024</pqid></control><display><type>article</type><title>A Case with Multiple Pathologies in the Pancreatic Head</title><source>Publicly Available Content Database</source><source>PubMed Central</source><source>Coronavirus Research Database</source><creator>Vujasinovic, Miroslav ; Ghazi, Sam ; Kartalis, Nikolaos ; Gustafsson Liljefors, Maria ; D'Souza, Melroy A ; Ghorbani, Poya ; Löhr, J-Matthias</creator><creatorcontrib>Vujasinovic, Miroslav ; Ghazi, Sam ; Kartalis, Nikolaos ; Gustafsson Liljefors, Maria ; D'Souza, Melroy A ; Ghorbani, Poya ; Löhr, J-Matthias</creatorcontrib><description>Autoimmune pancreatitis (AIP) type 1, paraduodenal (groove) pancreatitis, and follicular pancreatitis are rare clinical entities whose diagnosis may be challenging, given the potential imaging overlap with pancreatic cancer. We performed a retrospective analysis of the medical chart of a patient with multiple pancreas pathologies. We present a case with multiple pancreas pathologies, including a poorly differentiated ductal adenocarcinoma of pancreatobiliary type, an intraductal papillary mucinous lesion (pre-existing lesion of IPMN type), and an inflammatory process with complex features, in which paraduodenal (groove) pancreatitis, follicular pancreatitis, and IgG4-related pancreatitis (AIP type 1) were also present. The diagnosis of AIP and paraduodenal pancreatitis is not always straightforward, and in some cases, it is not easy to differentiate them from pancreatic cancer. Surgery should be considered in patients when a suspicion of malignant/premalignant lesions cannot be excluded after a complete diagnostic work-up.</description><identifier>ISSN: 2227-9059</identifier><identifier>EISSN: 2227-9059</identifier><identifier>DOI: 10.3390/biomedicines12081762</identifier><identifier>PMID: 39200226</identifier><language>eng</language><publisher>Switzerland: MDPI AG</publisher><subject>Abdomen ; Adenocarcinoma ; autoimmune pancreatitis ; Bile ducts ; Biopsy ; Cancer ; Case Report ; Comorbidity ; Cysts ; Diagnosis ; Endoscopy ; follicular pancreatitis ; Immunoglobulin G ; IPMN ; Kidney stones ; Kidneys ; Lesions ; Outpatient care facilities ; Pancreas ; Pancreatic cancer ; pancreatic ductal adenocarcinoma ; Pancreatitis ; paraduodenal pancreatitis ; Patients ; Phosphatase ; Small intestine ; Veins &amp; arteries</subject><ispartof>Biomedicines, 2024-08, Vol.12 (8), p.1762</ispartof><rights>COPYRIGHT 2024 MDPI AG</rights><rights>2024 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>2024 by the authors. 2024</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c449t-83a92dec197fcf7f724e6352d587b723e78b39097282d4dc1f526741d0add4b43</cites><orcidid>0000-0002-7647-198X ; 0000-0002-6496-295X ; 0000-0003-2102-7168</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.proquest.com/docview/3097881024/fulltextPDF?pq-origsite=primo$$EPDF$$P50$$Gproquest$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.proquest.com/docview/3097881024?pq-origsite=primo$$EHTML$$P50$$Gproquest$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,885,25751,27922,27923,37010,37011,38514,43893,44588,53789,53791,74182,74896</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/39200226$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Vujasinovic, Miroslav</creatorcontrib><creatorcontrib>Ghazi, Sam</creatorcontrib><creatorcontrib>Kartalis, Nikolaos</creatorcontrib><creatorcontrib>Gustafsson Liljefors, Maria</creatorcontrib><creatorcontrib>D'Souza, Melroy A</creatorcontrib><creatorcontrib>Ghorbani, Poya</creatorcontrib><creatorcontrib>Löhr, J-Matthias</creatorcontrib><title>A Case with Multiple Pathologies in the Pancreatic Head</title><title>Biomedicines</title><addtitle>Biomedicines</addtitle><description>Autoimmune pancreatitis (AIP) type 1, paraduodenal (groove) pancreatitis, and follicular pancreatitis are rare clinical entities whose diagnosis may be challenging, given the potential imaging overlap with pancreatic cancer. We performed a retrospective analysis of the medical chart of a patient with multiple pancreas pathologies. We present a case with multiple pancreas pathologies, including a poorly differentiated ductal adenocarcinoma of pancreatobiliary type, an intraductal papillary mucinous lesion (pre-existing lesion of IPMN type), and an inflammatory process with complex features, in which paraduodenal (groove) pancreatitis, follicular pancreatitis, and IgG4-related pancreatitis (AIP type 1) were also present. The diagnosis of AIP and paraduodenal pancreatitis is not always straightforward, and in some cases, it is not easy to differentiate them from pancreatic cancer. Surgery should be considered in patients when a suspicion of malignant/premalignant lesions cannot be excluded after a complete diagnostic work-up.</description><subject>Abdomen</subject><subject>Adenocarcinoma</subject><subject>autoimmune pancreatitis</subject><subject>Bile ducts</subject><subject>Biopsy</subject><subject>Cancer</subject><subject>Case Report</subject><subject>Comorbidity</subject><subject>Cysts</subject><subject>Diagnosis</subject><subject>Endoscopy</subject><subject>follicular pancreatitis</subject><subject>Immunoglobulin G</subject><subject>IPMN</subject><subject>Kidney stones</subject><subject>Kidneys</subject><subject>Lesions</subject><subject>Outpatient care facilities</subject><subject>Pancreas</subject><subject>Pancreatic cancer</subject><subject>pancreatic ductal adenocarcinoma</subject><subject>Pancreatitis</subject><subject>paraduodenal pancreatitis</subject><subject>Patients</subject><subject>Phosphatase</subject><subject>Small intestine</subject><subject>Veins &amp; arteries</subject><issn>2227-9059</issn><issn>2227-9059</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2024</creationdate><recordtype>article</recordtype><sourceid>COVID</sourceid><sourceid>PIMPY</sourceid><sourceid>DOA</sourceid><recordid>eNptklFvFCEQx4nR2Kb2GxiziS--XIWBXeDJXC5qm9Togz4TFoY7LnvLCbsav72cV2vPFB6YDP__D2YyhLxk9IpzTd_2Me3QRxdHLAyoYrKDJ-QcAORC01Y_fRCfkctStrQuzbhi4jk54xooBejOiVw2K1uw-RmnTfNpHqa4H7D5YqdNGtI6Ymni2EybQ2p0Ge0UXXON1r8gz4IdCl7enRfk24f3X1fXi9vPH29Wy9uFE0JPC8WtBo-OaRlckEGCwI634FslewkcpeprPVqCAi-8Y6GFTgrmqfVe9IJfkJsj1ye7Nfscdzb_MslG8yeR8trYXD81oLGMd47SlqGWwoHvZd9zpExb6i0NobLeHVn7ua_dczhO2Q4n0NObMW7MOv0wjPGWdS2vhDd3hJy-z1gms4vF4TDYEdNcDKdaMwFSQJW-_k-6TXMea68OKqkUoyD-qda2VhDHkOrD7gA1S0Urp1WdrqqrR1R1e9xFl0YMseZPDOJocDmVkjHcF8moOQyQeWyAqu3Vwwbdm_6OC_8N9_PBDQ</recordid><startdate>20240805</startdate><enddate>20240805</enddate><creator>Vujasinovic, Miroslav</creator><creator>Ghazi, Sam</creator><creator>Kartalis, Nikolaos</creator><creator>Gustafsson Liljefors, Maria</creator><creator>D'Souza, Melroy A</creator><creator>Ghorbani, Poya</creator><creator>Löhr, J-Matthias</creator><general>MDPI AG</general><general>MDPI</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>8FE</scope><scope>8FH</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>COVID</scope><scope>DWQXO</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>LK8</scope><scope>M7P</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><scope>5PM</scope><scope>DOA</scope><orcidid>https://orcid.org/0000-0002-7647-198X</orcidid><orcidid>https://orcid.org/0000-0002-6496-295X</orcidid><orcidid>https://orcid.org/0000-0003-2102-7168</orcidid></search><sort><creationdate>20240805</creationdate><title>A Case with Multiple Pathologies in the Pancreatic Head</title><author>Vujasinovic, Miroslav ; Ghazi, Sam ; Kartalis, Nikolaos ; Gustafsson Liljefors, Maria ; D'Souza, Melroy A ; Ghorbani, Poya ; Löhr, J-Matthias</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c449t-83a92dec197fcf7f724e6352d587b723e78b39097282d4dc1f526741d0add4b43</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2024</creationdate><topic>Abdomen</topic><topic>Adenocarcinoma</topic><topic>autoimmune pancreatitis</topic><topic>Bile ducts</topic><topic>Biopsy</topic><topic>Cancer</topic><topic>Case Report</topic><topic>Comorbidity</topic><topic>Cysts</topic><topic>Diagnosis</topic><topic>Endoscopy</topic><topic>follicular pancreatitis</topic><topic>Immunoglobulin G</topic><topic>IPMN</topic><topic>Kidney stones</topic><topic>Kidneys</topic><topic>Lesions</topic><topic>Outpatient care facilities</topic><topic>Pancreas</topic><topic>Pancreatic cancer</topic><topic>pancreatic ductal adenocarcinoma</topic><topic>Pancreatitis</topic><topic>paraduodenal pancreatitis</topic><topic>Patients</topic><topic>Phosphatase</topic><topic>Small intestine</topic><topic>Veins &amp; arteries</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Vujasinovic, Miroslav</creatorcontrib><creatorcontrib>Ghazi, Sam</creatorcontrib><creatorcontrib>Kartalis, Nikolaos</creatorcontrib><creatorcontrib>Gustafsson Liljefors, Maria</creatorcontrib><creatorcontrib>D'Souza, Melroy A</creatorcontrib><creatorcontrib>Ghorbani, Poya</creatorcontrib><creatorcontrib>Löhr, J-Matthias</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Natural Science Collection</collection><collection>ProQuest One Community College</collection><collection>Coronavirus Research Database</collection><collection>ProQuest Central Korea</collection><collection>ProQuest Central Student</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Biological Science Collection</collection><collection>Biological Science Database</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><collection>DOAJ Directory of Open Access Journals</collection><jtitle>Biomedicines</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Vujasinovic, Miroslav</au><au>Ghazi, Sam</au><au>Kartalis, Nikolaos</au><au>Gustafsson Liljefors, Maria</au><au>D'Souza, Melroy A</au><au>Ghorbani, Poya</au><au>Löhr, J-Matthias</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>A Case with Multiple Pathologies in the Pancreatic Head</atitle><jtitle>Biomedicines</jtitle><addtitle>Biomedicines</addtitle><date>2024-08-05</date><risdate>2024</risdate><volume>12</volume><issue>8</issue><spage>1762</spage><pages>1762-</pages><issn>2227-9059</issn><eissn>2227-9059</eissn><abstract>Autoimmune pancreatitis (AIP) type 1, paraduodenal (groove) pancreatitis, and follicular pancreatitis are rare clinical entities whose diagnosis may be challenging, given the potential imaging overlap with pancreatic cancer. We performed a retrospective analysis of the medical chart of a patient with multiple pancreas pathologies. We present a case with multiple pancreas pathologies, including a poorly differentiated ductal adenocarcinoma of pancreatobiliary type, an intraductal papillary mucinous lesion (pre-existing lesion of IPMN type), and an inflammatory process with complex features, in which paraduodenal (groove) pancreatitis, follicular pancreatitis, and IgG4-related pancreatitis (AIP type 1) were also present. The diagnosis of AIP and paraduodenal pancreatitis is not always straightforward, and in some cases, it is not easy to differentiate them from pancreatic cancer. Surgery should be considered in patients when a suspicion of malignant/premalignant lesions cannot be excluded after a complete diagnostic work-up.</abstract><cop>Switzerland</cop><pub>MDPI AG</pub><pmid>39200226</pmid><doi>10.3390/biomedicines12081762</doi><orcidid>https://orcid.org/0000-0002-7647-198X</orcidid><orcidid>https://orcid.org/0000-0002-6496-295X</orcidid><orcidid>https://orcid.org/0000-0003-2102-7168</orcidid><oa>free_for_read</oa></addata></record>
fulltext fulltext
identifier ISSN: 2227-9059
ispartof Biomedicines, 2024-08, Vol.12 (8), p.1762
issn 2227-9059
2227-9059
language eng
recordid cdi_doaj_primary_oai_doaj_org_article_a136c0051e974c2db7bb3e019a0da0ff
source Publicly Available Content Database; PubMed Central; Coronavirus Research Database
subjects Abdomen
Adenocarcinoma
autoimmune pancreatitis
Bile ducts
Biopsy
Cancer
Case Report
Comorbidity
Cysts
Diagnosis
Endoscopy
follicular pancreatitis
Immunoglobulin G
IPMN
Kidney stones
Kidneys
Lesions
Outpatient care facilities
Pancreas
Pancreatic cancer
pancreatic ductal adenocarcinoma
Pancreatitis
paraduodenal pancreatitis
Patients
Phosphatase
Small intestine
Veins & arteries
title A Case with Multiple Pathologies in the Pancreatic Head
url http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-14T11%3A24%3A47IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-gale_doaj_&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=A%20Case%20with%20Multiple%20Pathologies%20in%20the%20Pancreatic%20Head&rft.jtitle=Biomedicines&rft.au=Vujasinovic,%20Miroslav&rft.date=2024-08-05&rft.volume=12&rft.issue=8&rft.spage=1762&rft.pages=1762-&rft.issn=2227-9059&rft.eissn=2227-9059&rft_id=info:doi/10.3390/biomedicines12081762&rft_dat=%3Cgale_doaj_%3EA807425869%3C/gale_doaj_%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c449t-83a92dec197fcf7f724e6352d587b723e78b39097282d4dc1f526741d0add4b43%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=3097881024&rft_id=info:pmid/39200226&rft_galeid=A807425869&rfr_iscdi=true