Idiopathic intracranial hypertension associated with anaemia, secondary to antiretroviral drug in a human immunodeficiency virus positive patient

Papilledema in a patient with human immunodeficiency virus (HIV)/acquired immune deficiency syndrome is an alarming finding. Any condition giving rise to raised intracranial tension (ICT) can cause papilledema, and in these patients, it could be secondary to opportunistic infections like meningitis...

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Bibliographic Details
Published in:Indian journal of ophthalmology 2018-01, Vol.66 (1), p.168-169
Main Authors: Ananth, J Vijay, Sudharshan, S, Selvakumar, Ambika, Devaleenal, Bella J, Kalaivani, Kavitha, Biswas, Jyotirmay
Format: Article
Language:English
Subjects:
Acquired immune deficiency syndrome
AIDS
anaemia
Anemia
Antiretroviral agents
antiretroviral drug
Antiretroviral drugs
Antiretroviral therapy
Case Reports
Consent
Dosage and administration
Drug therapy
Edema
Health aspects
Hematology
Highly active antiretroviral therapy
HIV
HIV patients
Human immunodeficiency virus
Hypertension
idiopathic intracranial hypertension
Intracranial hypertension
Iron
Meningitis
NMR
Nuclear magnetic resonance
Ophthalmology
Optic nerve
papilledema
Patients
Retina
Sinuses
Swelling
Thrombosis
Zidovudine
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Summary:Papilledema in a patient with human immunodeficiency virus (HIV)/acquired immune deficiency syndrome is an alarming finding. Any condition giving rise to raised intracranial tension (ICT) can cause papilledema, and in these patients, it could be secondary to opportunistic infections like meningitis to neoplasm. We report a case of a 28-year old female with HIV on antiretroviral therapy, who presented to us, with papilledema. Her fundus examination revealed superficial hemorrhages and Roth's spots along with papilledema. Patient was diagnosed with idiopathic intracranial hypertension (IIH), and all other possible systemic associations were ruled out. Her blood tests showed severe anemia. The papilledema and retinal changes resolved with treatment of anemia. This is a rare presentation of IIH in HIV positive patient due to anemia, secondary to zidovudine adverse effect.
ISSN:0301-4738
1998-3689
DOI:10.4103/ijo.IJO_592_17