Bacterial community of chronic rhinosinusitis patients and therapeutic ultrasound efficacy: clinical trial study

• Published in: Iranian journal of microbiology 2022-06, Vol.14 (3), p.313-318
• Main Authors: Feizabadi, Narjes, Sarrafzadeh, Javad, Fathali, Mojtaba, Vasaghi-Gharamaleki, Behnoosh, Dadgoo, Mahdi, Kardan-Yamchi, Jalil, Kazemian, Hossein, Hesam-Shariati, Sonia, Feizabadi, Mohammad Mehdi
• Format: Article
• Language: English
• Subjects: Bacterial infection; Computed tomography scan; Original; Rhinosinusitis; Treatment; Ultrasound therapy
• ISSN: 2008-3289; 2008-4447
• DOI: 10.18502/ijm.v14i3.9765

Bacterial involvement in chronic rhinosinusitis (CRS) condition made it difficult to treat using available antibiotic therapy. Therapeutic ultrasound was investigated here to evaluate bacterial diversity and quantity before and after continuous/pulsed ultrasound strategy compared to control patients. Totally, 34 CRS patients were studied in three groups, including continuous ultrasound, pulsed ultrasound and control. Bacterial culture and identification were done before and after treatment. Computed tomography scan (CT scan) and questionnaire scores were recorded two times before and after intervention. The most prevalent bacterial isolates were non-hemolytic (34 patients), coagulase-negative (33 patients), Gram-negative cocci (26 patients), (19 patients), (five patients) and (five patients). Both continuous and pulsed ultrasound could significantly reduce the quantity of bacterial isolates after treatment. CT scan and questionnaire results support the effectiveness of therapeutic ultrasound. The quantity of clinically important bacteria was significantly reduced using ultrasound treatment and recovery of patients was supported by CT scan and questionnaire scores. Alternative therapeutic ultrasound could be an effective procedure in CRS patients.