Incidence and Survival of Pediatric Soft Tissue Sarcomas in Moscow Region, Russian Federation, 2000-2009

• Published in: Complexity (New York, N.Y.) N.Y.), 2012, Vol.2012 (2012), p.184-189
• Main Authors: Shamanskaya, T. V., Abdullaev, R. T., Dobrenkov, K. V., Kachanov, D. Y., Varfolomeeva, S. R.
• Format: Article
• Language: English
• ISSN: 1357-714X; 1076-2787; 1099-0526; 1369-1643
• DOI: 10.1155/2012/350806

The aim of the study was to assess the incidence and survival rates of soft tissue sarcomas (STSs) in children 0–14 years of age in Moscow Region, Russian Federation. The database of childhood population-based cancer registry of Moscow Region was used as a data source. Tumors were stratified according to International Classification of Childhood Cancer, 3d ed. Sixty-eight cases of STS were registered from 2000 to 2009. Crude incidence rate was 0,78, and age-standardized incidence rate using World Standard Population was 0,81 per 100.000 children/year. The highest age-specific incidence was observed in infants: 1,76 per 100.000 children/year. Rhabdomyosarcoma (RMS) was the most common histological type comprising 54,4% of all STS. 5-year observed survival (OS) of all patients with STS was 64,1 (95% CI 55,0–73,2). There was no statistically significant difference in OS between RMS—59,2 (95% CI 47,0–71,4) and nonrhabdomyosarcoma STS—69,3 (95% CI 55,8–82,8) (P=0.63). Incidence and survival rates of STS observed in the study were comparable to the other Eastern European countries.