Evaluation of carcinogenic risk of heavy metals due to consumption of rice in Southwestern Iran

• Published in: Toxicology reports 2024-06, Vol.12, p.578-583
• Main Authors: Mohammadi, Mohammad Javad, Kiani, Fatemeh, Farhadi, Majid, Ghanbari, Saeed, Jalili, Davood, Mirzaei, Leila
• Format: Article
• Language: English
• Subjects: Carcinogenic risk; Heavy metals; Iran; Rice
• ISSN: 2214-7500; 2214-7500
• DOI: 10.1016/j.toxrep.2024.05.005

Pollution by heavy metals is a serious global problem due to its toxicity, abiotic characteristics, abundant sources, and cumulative behavior. On the other hand, considering the importance of rice consumption as an important part of nutrition in Lordegan and Ahvaz cities, this study was conducted to evaluate the carcinogenic risk of heavy metals lead, cadmium, zinc, nickel and in local Champa rice cultivated in these two cities. 16 Champa rice samples were collected from the fields of Lordegan and Ahvaz cities. The elements were read in three replicates by Varian 710-ES atomic emission device. The results showed that the concentration of cadmium and nickel in the cultivated rice in the two studied cities was within the range of the national standard of Iran and the Codex standard. Carcinogenic risk values for lead, cadmium and nickel in Champa Lordegan and Ahvaz rice were within the safe range. Also, the non-carcinogenic risk for these heavy metals in the two studied areas was less than 1 and was in the safe range. Rice pollution in Champa in Ahvaz can be due to the industrial nature of this city, and in Lordegan, it is due to pollution through pesticides, chemical fertilizers, and transportation. Long-term consumption of contaminated rice may endanger the health of residents of these areas. It is recommended to carry out regular and up-to-date monitoring strategies in these two cities to prevent the entry of these toxic heavy metals into the human food chain. Also, more studies are needed to evaluate the complete scenario and make definitive decisions. [Display omitted] •The concentration of cadmium and nickel was within the range of the Codex standard.•The lead concentration in Lordegan and Ahvaz was higher than the standard.•Carcinogenic risk values in rice were within the probable risk range.•The carcinogenic risk of nickel metal was in the dangerous range in two regions.