Analysis of diagnostic criteria in adamantiades-behçet disease: A retrospective study

• Published in: Indian journal of dermatology 2013-07, Vol.58 (4), p.275-277
• Main Authors: di Meo, Nicola, Bergamo, S, Vidimari, P, Bonin, S, Trevisan, G
• Format: Article
• Language: English
• Subjects: Behcet; Behcet's disease; Care and treatment; Diagnosis; international criteria for Behçet′s disease; international study group for Behηet disease; Original; Patient outcomes; Risk factors
• ISSN: 0019-5154; 1998-3611
• DOI: 10.4103/0019-5154.113936

Adamantiades-Behçet′s disease (ABD) is a chronic-relapsing, inflammatory and multi-systemic disease. Any organ or system may be involved: ABD presents a great variety of cutaneous and mucosal lesions, ocular manifestations, central and peripheral nervous system abnormalities, joint as well as gastrointestinal involvement. Since clear pathognomonic clinical features and laboratory tests are lacking, the diagnosis of ABD mainly relies on the characteristic clinical features. Several sets of diagnostic criteria have been used. The International Study Group for Behηet Disease (ISGBD) in 1990 formulated a set of criteria to warrant uniformity of both diagnosis and classification. Therefore, in 2006, a new set was proposed by the International Team for the Revision of the International Criteria for Behηet′s Disease (ITR-ICBD) not only to uniform the previous criteria but also to establish best accuracy, along with an optimum sensivity and specificity. The aims of this study are both to analyze the clinical features of ABD patients and to validate the ISGBD and ITR-ICDB criteria for the diagnosis of ABD in our cohort.