Long Time from Diagnosis to Surgery May Increase Postoperative Complication Rates in Elective CD Intestinal Resections: An Observational Study

Background. There is lack of data analyzing short-term postoperative complications and time from diagnosis to surgery in Crohn’s disease (CD). Aim. To compare complication rates after elective abdominal operations in CD patients with different durations of disease. Methods. Retrospective observation...

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Bibliographic Details
Published in:Gastroenterology research and practice 2018-01, Vol.2018 (2018), p.1-6
Main Authors: Coy, Cláudio Saddy Rodrigues, Yamamoto, Takayuki, Spinelli, Antonino, Martinez, Carlos Augusto Real, Magro, Daniela Oliveira, Kotze, Paulo Gustavo, Warusavitarne, Janindra
Format: Article
Language:English
Subjects:
Abdomen
Adalimumab
Biological products
Comparative analysis
Complications and side effects
Fistula
Gastroenterology
Laparoscopy
Medical research
Medicine, Experimental
Observational studies
Patients
Statistics
Studies
Surgery
Surgical outcomes
Systematic review
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Summary:Background. There is lack of data analyzing short-term postoperative complications and time from diagnosis to surgery in Crohn’s disease (CD). Aim. To compare complication rates after elective abdominal operations in CD patients with different durations of disease. Methods. Retrospective observational study with CD patients who submitted to elective intestinal resections. Patients were allocated in 2 groups according to time to surgery (TS) in less or more than 5 years. Short-term postoperative complications were analyzed and compared between the 2 groups, and binary logistic regression analysis was performed to check for significant variables. Results. 123 patients were finally included, 77 with TS > 5 years (62.6%) and 46 with TS  5 years had higher rates of overall surgical complications (p=0.011), reoperations (p=0.003), surgical site infections (p=0.014), anastomotic dehiscence (p=0.021), abdominal abscesses (p=0.021), and overall medical complications (p=0.019). On logistic regression, the single significant variable was the confection of stomas (OR: 3.203; 95% CI: 1.011–10.151; p=0.048). Conclusions. Patients with longer time to surgery showed a significant increase in overall medical and surgical postoperative early complications after elective intestinal resections.
ISSN:1687-6121
1687-630X
DOI:10.1155/2018/4703281