Anesthesia management of CRS and HIPEC in advanced ovarian cancer with ultra-high intra-abdominal pressure: a case report

Cytoreductive surgery (CRS) combined with hyperthermic intraperitoneal chemotherapy (HIPEC) is a leading treatment for advanced ovarian cancer, significantly improving overall survival and disease-free survival. This case involves a patient with peritoneal metastasis and ultra-high intra-abdominal p...

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Bibliographic Details
Published in:Frontiers in oncology 2024-11, Vol.14, p.1449171
Main Authors: Chen, Suli, Lin, Yanjun, Gao, Shuncai, Liu, Shuo, Yang, Zhanmin, Ma, Ruiqing, Lu, Liangyuan
Format: Article
Language:English
Subjects:
anesthetic management
cytoreductive surgery
goal-directed fluid therapy
hyperthermic intraperitoneal chemotherapy
intra-abdominal hypertension
Oncology
ovarian cancer
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Summary:Cytoreductive surgery (CRS) combined with hyperthermic intraperitoneal chemotherapy (HIPEC) is a leading treatment for advanced ovarian cancer, significantly improving overall survival and disease-free survival. This case involves a patient with peritoneal metastasis and ultra-high intra-abdominal pressure (36 mmHg). CRS + HIPEC induces extensive pathological and physiological changes affecting respiratory, circulatory, renal, coagulation, and metabolic systems. Effective perioperative anesthesia management, including the type and volume of fluids administered, is crucial for optimizing patient outcomes. The complexities of anesthesia management in such cases present significant challenges.
ISSN:2234-943X
2234-943X
DOI:10.3389/fonc.2024.1449171