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Antibodies against Borrelia burgdorferi Sensu Lato in Clinically Healthy and Sick Horses: First Report from the Czech Republic

Lyme disease, caused by some strains of bacterial spirochetes sensu lato ( sl), affects humans but also domestic animals including horses. The primary pathogens in horses in Europe are , and sensu stricto. To our knowledge, there are no data available on the seropositivity of s.l. in horses from the...

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Published in:Microorganisms (Basel) 2023-06, Vol.11 (7), p.1706
Main Authors: Kasparkova, Nikola, Bartova, Eva, Zakovska, Alena, Budikova, Marie, Sedlak, Kamil
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description Lyme disease, caused by some strains of bacterial spirochetes sensu lato ( sl), affects humans but also domestic animals including horses. The primary pathogens in horses in Europe are , and sensu stricto. To our knowledge, there are no data available on the seropositivity of s.l. in horses from the Czech Republic. In this country, horses are mainly used for sport, breeding, and recreational riding in areas where vectors of s.l. are present, which is why they are frequently at risk of infection. The aim of the study was to detect anti-borrelia IgM and IgG antibodies in clinically healthy and sick horses from the Czech Republic and to evaluate the risk factors of infection. In total, sera of 262 horses (247 clinically healthy horses and 15 horses hospitalized due to symptoms of encephalitis/meningoencephalitis) were examined by an indirect sandwich enzyme-linked immunosorbent assay. Positivity of was 27% (66/247) in clinically healthy horses (21% IgM, 7% IgG and 3% IgM + IgG antibodies) and 20% (3/15) in horses with clinical signs (20% IgM, 7% IgG and 7% IgM + IgG). In the clinically healthy horses, positivity statistically differed ( ≤ 0.05) only in Pony and Warmblood breeds, being the most affected at 32% and 30%, respectively, while other characteristics (sex, age, usage and localities) had no effect on positivity. This is the first survey of antibodies to s.l. in Czech horses showing that horses are exposed to ticks infected with s.l. This should be taken into account when making differential diagnoses in patients with non-specific symptoms to start with adequate therapy.
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subjects Antibodies
Arachnids
Borrelia burgdorferi
borreliosis
Cluster analysis
Diagnosis
Domestic animals
ELISA
Encephalitis
Enzyme-linked immunosorbent assay
Enzymes
equine
Health aspects
Health risks
Horses
Identification and classification
Immunoglobulin G
Immunoglobulin M
Infections
Lyme disease
Lyme diseases
Measurement
Meningitis
Meningoencephalitis
Physiological aspects
Recreation areas
Risk factors
Signs and symptoms
Spirochetes
Testing
Ticks
Vector-borne diseases
Vectors
Viral antibodies
title Antibodies against Borrelia burgdorferi Sensu Lato in Clinically Healthy and Sick Horses: First Report from the Czech Republic
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