Integrated High-Throughput Centrifugal Microfluidic Chip Device for Pathogen Detection On-Site

An integrated and high-throughput device for pathogen detection is crucial in point-of-care testing (POCT), especially for early diagnosis of infectious diseases and preventing the spread of infection. We developed an on-site testing platform that utilizes a centrifugal microfluidic chip and automat...

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Bibliographic Details
Published in:Biosensors (Basel) 2024-06, Vol.14 (6), p.313
Main Authors: Lu, Shuyu, Yang, Yuanzhan, Cui, Siqi, Li, Anyi, Qian, Cheng, Li, Xiaoqiong
Format: Article
Language:English
Subjects:
Acids
Adsorption
Automation
Biosensing Techniques
Centrifugal force
centrifugal microfluidic chip
Centrifugation
Controllers
Design
Diagnosis
E coli
Efficiency
Electromagnetic fields
Electromagnetism
Escherichia coli - isolation & purification
Gene amplification
Humans
hydrophobic valve
Infectious diseases
Lab-On-A-Chip Devices
lamp
Limit of Detection
Lysis
Microfluidics
Molecular Diagnostic Techniques
Nucleic Acid Amplification Techniques
nucleic acid extraction
Nucleic acids
Onsite
paraffin valve
Pathogens
Polymethyl methacrylate
Portable equipment
Power consumption
Power management
Reagents
Real time
siphon valve
Valves
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Summary:An integrated and high-throughput device for pathogen detection is crucial in point-of-care testing (POCT), especially for early diagnosis of infectious diseases and preventing the spread of infection. We developed an on-site testing platform that utilizes a centrifugal microfluidic chip and automated device to achieve high-throughput detection. The low-power (
ISSN:2079-6374
2079-6374
DOI:10.3390/bios14060313