Auxiliary role of Fisher discriminant function based on inflammatory cytokines in diagnosis of depressive disorder

BackgroundCurrently， the diagnosis of depressive disorder relies on symptomatology， which is greatly influenced by subjective factors such as clinicians' experience. Finding more accurate and reliable quantitative diagnostic methods is currently an urgent problem.ObjectiveTo explore the value o...

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Bibliographic Details
Published in:Sichuan Jingshen Weisheng 2024-08, Vol.37 (4), p.312-316
Main Authors: Jia Hailing, Yang Yongtao, Cui Lijun, Guo Yanmei, Yan Baoping, Cui Wei, Sun Xiuli
Format: Article
Language:Chinese
Subjects:
depressive disorder
diagnosis
fisher discriminant function
inflammatory cytokines
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Summary:BackgroundCurrently， the diagnosis of depressive disorder relies on symptomatology， which is greatly influenced by subjective factors such as clinicians' experience. Finding more accurate and reliable quantitative diagnostic methods is currently an urgent problem.ObjectiveTo explore the value of Fisher discriminant function based on inflammatory cytokines in the diagnosis of depressive disorder， so as to provide references for clinical diagnosis.MethodsA total of 136 patients diagnosed with depressive disorder according to the Diagnostic and Statistical Manual of Mental Disorders， fifth edition （DSM-5） criteria， who underwent inpatient treatment at Hebei Mental Health Center from April 2020 to November 2020， were enrolled as study group. 67 healthy participants matched for age and gender， was recruited during the same period. Serum levels of inflammatory cytokine were measured using enzyme-linked immunosorbent assay（ELISA）. Fisher discriminant model was employed to establish a discriminant function for inflam
ISSN:1007-3256
DOI:10.11886/scjsws20230815004