Unusual presentation of generalized macular amyloidosis in a young adult

Macular amyloidosis is a common problem seen dermatology out-patient department. Generalized macular amyloidosis presenting with a poikilodermatous appearance is rare. In our case, an 18-year-old male presented with generalized hypopigmented macules with a poikilodermatous appearance of 10-year dura...

Full description

Saved in:
Bibliographic Details
Published in:Indian journal of dermatology 2008-10, Vol.53 (4), p.201-203, Article 201
Main Authors: Kudur, Mohan H, Sathish, Pai B, Sripathi, H, Prabhu, Smitha
Format: Article
Language:English
Subjects:
Amyloidosis
Case Report
Case studies
Congenital diseases
congo red stain
Diagnosis
DNA repair
Generalized macular amyloidosis
Health aspects
Keratosis
Medical diagnosis
poikilodermatous appearance
Young adults
Citations: Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Macular amyloidosis is a common problem seen dermatology out-patient department. Generalized macular amyloidosis presenting with a poikilodermatous appearance is rare. In our case, an 18-year-old male presented with generalized hypopigmented macules with a poikilodermatous appearance of 10-year duration. His developmental milestones were normal with negative family history of similar complaints. Histopathology of hyperpigmented lesions revealed hyperkeratosis and acanthosis of epidermis and hypopigmented lesion showing only hyperkeratosis. Both lesions were showing the deposition of amorphous, hazy material in the tips of papillary dermis with perivascular inflammatory infiltrate. Congo red staining of the amorphous material was positive for amyloid.
ISSN:0019-5154
1998-3611
DOI:10.4103/0019-5154.44802