Prevalence of Sarcopenia and Its Effect on Postoperative Complications in Patients with Crohn’s Disease

Background and Aims. Sarcopenia is a prognostic factor of outcomes for various diseases, but reports on sarcopenia in patients with Crohn’s disease (CD) are few. We aim to determine the prevalence of sarcopenia and assess the role of sarcopenia in postoperative complications in patients with CD at a...

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Bibliographic Details
Published in:Gastroenterology research and practice 2021, Vol.2021, p.3267201-8
Main Authors: Zhang, Chen, Yu, Dingye, Hong, Liwen, Zhang, Tianyu, Liu, Hua, Fan, Rong, Wang, Lei, Zhong, Jie, Wang, Zhengting
Format: Article
Language:English
Subjects:
Abdomen
Abscesses
Age
Albumin
Analysis
Body mass index
Cancer
Care and treatment
Complications
Health aspects
Hemoglobin
Hospitals
Laparoscopy
Muscles
Musculoskeletal system
Ostomy
Overweight
Patients
Postoperative period
Prognosis
Risk factors
Sarcopenia
Surgery
Surgical outcomes
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Summary:Background and Aims. Sarcopenia is a prognostic factor of outcomes for various diseases, but reports on sarcopenia in patients with Crohn’s disease (CD) are few. We aim to determine the prevalence of sarcopenia and assess the role of sarcopenia in postoperative complications in patients with CD at a tertiary referral center. Methods. Patients who underwent intestinal surgery for CD from January 2013 to October 2019 were retrospectively enrolled. The L3 skeletal muscle mass index (SMI) was used to identify sarcopenia. Demographic data, preoperative laboratory data, surgical details, and hospital outcomes were recorded. The factors associated with postoperative complications were evaluated through univariate and multivariate analyses. Results. One hundred and twenty-four patients were enrolled. Thirty-four of them (27.4%), including 11 males, were diagnosed with sarcopenia. Compared with patients without sarcopenia, sarcopenic patients had a significantly lower BMI (P
ISSN:1687-6121
1687-630X
DOI:10.1155/2021/3267201