Solvothermal Synthesis of LaF3:Ce Nanoparticles for Use in Medicine: Luminescence, Morphology and Surface Properties

A series of LaF3:Ce3+ phosphors for application in photodynamic therapy are synthesized using a one-stage solvothermal synthesis. The synthesis conditions; type and quantity of stabilizer; concentration of activator providing the maximum intensity of UV- and X-ray-excited luminescence; lowest size;...

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Bibliographic Details
Published in:Ceramics 2023-03, Vol.6 (1), p.492-503
Main Authors: Dorokhina, Anastasiia, Ishihara, Ryoya, Kominami, Hiroko, Bakhmetyev, Vadim, Sychov, Maxim, Aoki, Toru, Morii, Hisashi
Format: Article
Language:English
Subjects:
Biocompatibility
Cerium
Ethanol
Fluorides
Laboratories
LaF3:Ce
Lanthanum fluorides
Localization
Luminescence
Nanocomposites
Nanocrystals
Nanoparticles
PEG
Phosphors
Photodynamic therapy
Polyethylene glycol
Polyvinylpyrrolidone
PVP
Radiation
Software
solvothermal synthesis
Stabilizers (agents)
Surface properties
Synthesis
X-ray luminescence
zeta-potential
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Summary:A series of LaF3:Ce3+ phosphors for application in photodynamic therapy are synthesized using a one-stage solvothermal synthesis. The synthesis conditions; type and quantity of stabilizer; concentration of activator providing the maximum intensity of UV- and X-ray-excited luminescence; lowest size; and highest colloidal stability of the phosphor nanoparticles are found. As a result of this study, the following parameters are determined using cerium content 5% mol. ethanol as the reaction medium for the solvothermal synthesis and polyvinylpyrrolidone as the stabilizer at an optimized amount.
ISSN:2571-6131
2571-6131
DOI:10.3390/ceramics6010028