A Study of Phenolic Bioactive Compounds Of Daucus Carota Subsp. Sativus Fruits of Yaskrava, Nantska Kharkivska and Olenka Species and Of Dauci Carotae Subsp. Sativi Fructuum Extractum Siccum

The objective of the work was to study the qualitative composition and determine the quantitative content of phenolic compounds of Daucus carota subsp. sativus fruits of Yaskrava, Nantska Kharkivska and Olenka species and of Dauci carotae subsp. sativi fructuum extractum siccum. Phenolic compounds w...

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Bibliographic Details
Published in:EUROPEAN PHARMACEUTICAL JOURNAL 2022-01, Vol.69 (1), p.16-26
Main Authors: Kyslychenko, V., Protska, V, Horiacha, L, Liaudanskas, M, Zvikas, V, Trumbeckaite, S, Ivanauskas, L, Jakstas, V, Kyslychenko, O, Zhuravel, I, Andriukova, L, Filyanina, N
Format: Article
Language:English
Subjects:
antioxidant activity
Antioxidants
Apoptosis
Bioavailability
Cardiomyocytes
Cardiovascular disease
daucus carota subsp. sativus
Endothelium
Enzymes
Experiments
Flavonoids
Free radicals
Heart
Hydrogen
Hypertension
Lipids
Medical research
Nitrogen
Oxidation
Oxidative stress
phenolic compounds
uplc-esi-ms/ms
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Summary:The objective of the work was to study the qualitative composition and determine the quantitative content of phenolic compounds of Daucus carota subsp. sativus fruits of Yaskrava, Nantska Kharkivska and Olenka species and of Dauci carotae subsp. sativi fructuum extractum siccum. Phenolic compounds were studied by UPLC-ESI-MS/MS method. High content of phenol-origin bioactive substances was fixed in Daucus carota subsp. sativus fruits of Nantska Kharkivska variety (363.19 μg/g). Dominating compounds were chlorogenic acid, cynaroside, rutin and hyperoside. Daucus carota subsp. sativus fruits of all study species under question were found to possess permanent qualitative composition of phenolic compounds, whereas their quantitative content in experimental samples differed slightly. The results of analysis confirm promising development of novel antioxidant and cardioprotective drugs on the basis of Dauci carotae subsp. sativi fructuum extractum siccum.
ISSN:2453-6725
2453-6725
DOI:10.2478/afpuc-2022-0002