A Case of Parvovirus-Related Haemophagocytic Lymphohistiocytosis in a Patient with HbH Disease

Hemophagocytic lymphohistiocytosis (HLH) is rare and life-threatening medical emergency. Parvovirus infection is rarely associated with HLH. We report a case of parvovirus-related HLH in a patient with alpha thalassaemia (HbH disease). The patient responded well to a course of dexamethasone without...

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Bibliographic Details
Published in:Case reports in medicine 2018-01, Vol.2018 (2018), p.1-4
Main Authors: Fan, Bingwen Eugene, Kuthiah, Navin, Chong, Chern Hao, Cheong, Nicholas wong wai, Hussain, Ikram, Er, Chaozer, Meyyur Aravamudan, Veeraraghavan, En-Xian Tan, Emily
Format: Article
Language:English
Subjects:
Abdomen
Anemia
Blood
Blood diseases
Bone marrow
Case Report
Case reports
Cytomegalovirus
Dexamethasone
Disease
Etoposide
Fever
Hemoglobin
Histiocytosis
Infections
Iron
Lymphocytosis
Parvoviruses
Transplants & implants
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Summary:Hemophagocytic lymphohistiocytosis (HLH) is rare and life-threatening medical emergency. Parvovirus infection is rarely associated with HLH. We report a case of parvovirus-related HLH in a patient with alpha thalassaemia (HbH disease). The patient responded well to a course of dexamethasone without the need of etoposide. Based on our literature search, this is the first case of parvovirus related HLH in a patient with HbH disease in the medical literature.
ISSN:1687-9627
1687-9635
DOI:10.1155/2018/8057045