Efficacy of the cigarette-burning application combined with medication intervention for smoking cessation in China: A randomized controlled trial

• Published in: Digital health 2024-01, Vol.10, p.20552076241297732
• Main Authors: Wei, Xiao-Wen, Qin, Rui, Liu, Yong-Zhuang, Liu, Zhao, Cheng, An-Qi, Zhou, Xin-Mei, Su, Zheng, Cui, Zi-Yang, Li, Jin-Xuan, Zhao, Liang, Xiao, Dan, Wang, Chen
• Format: Article
• Language: English
• Subjects: Abstinence; Cigarettes; Intervention; New ways to improve the effectiveness of health apps and web-intervention; Smartphones; Smoking cessation
• ISSN: 2055-2076; 2055-2076
• DOI: 10.1177/20552076241297732

Background Although smartphone application for smoking cessation was considered a promising strategy, there were scarce studies on the combination of usual interventions and apps for smoking cessation in China. Our study aimed to evaluate the efficacy of the Cigarette-Burning application combined with medication intervention for smoking cessation. Methods A parallel, open-label randomized clinical trial was conducted with a ratio of 1:1 allocation into the bupropion plus app group and bupropion group. All participants received bupropion intervention. Besides, participants in the bupropion plus app group were required to download and use the Cigarette-Burning app. Follow-up visits were conducted at weeks 1, 2, 4, 9, 12, and 24 after initiation of treatment. Results Four hundred participants were eventually included and analyzed from July 2019 to June 2021. The continuous abstinence rate at 9–12 weeks was significantly higher in the bupropion plus app group (39.5%) than in the bupropion group (27.5%) (OR = 1.64, 95% CI: 1.04–2.60, p  5, age at starting smoking ≤ 18 (p