The Clinical Anatomy of SARS-CoV-2 Variants of Concern in Central Greece During October 2020-July 2022

The emergence of SARS-CoV-2 variants of concern (VOCs) during the COVID-19 pandemic necessitates investigation into their clinical differentiation and outcomes. This study aimed to examine these differences among VOCs, considering multiple related factors. An observational cohort study was conducted...

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Bibliographic Details
Published in:Microorganisms (Basel) 2024-12, Vol.12 (12), p.2573
Main Authors: Voulgaridi, Ioanna, Bogogiannidou, Zacharoula, Dadouli, Katerina, Galanopoulos, Achilleas P, Kyritsi, Maria A, Vontas, Alexandros, Matziri, Alexia, Kola, Konstantina, Vachtsioli, Evangelia, Anagnostopoulos, Lemonia, Tsispara, Anastasia, Oikonomou, Katerina G, Babalis, Dimitris, Petinaki, Efthymia, Tseroni, Maria, Kalala, Fani, Speletas, Matthaios, Mouchtouri, Varvara A, Hadjichristodoulou, Christos
Format: Article
Language:English
Subjects:
Adults
Children
Comorbidity
COVID-19
COVID-19 vaccines
differences in severity
differences in symptomatology
Disease transmission
Drug dosages
Dyspnea
Emergency medical care
Emergency medical services
Epidemiology
Genetic engineering
Global health
Hospitalization
Immune system
Infection
Infections
Interviews
Intubation
Laboratories
Medical history
Medical records
Medical research
Medicine, Experimental
Observational studies
Olfaction
outcomes of COVID-19
Pandemics
Patients
Pneumonia
Proteins
Public health
Regression analysis
Respiration
SARS-CoV-2
Severe acute respiratory syndrome coronavirus 2
Signs and symptoms
Vaccination
variants of concern (VOCs)
Viral diseases
Virulence
Viruses
Citations: Items that this one cites
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Description
Summary:The emergence of SARS-CoV-2 variants of concern (VOCs) during the COVID-19 pandemic necessitates investigation into their clinical differentiation and outcomes. This study aimed to examine these differences among VOCs, considering multiple related factors. An observational cohort study was conducted on patients diagnosed with SARS-CoV-2 infection via nasopharyngeal/oropharyngeal swab who visited the emergency department of a public Greek hospital between October 2020 and July 2022 during different VOC circulation in the region. Data on clinical manifestations, outcomes, and medical history (comorbidities, prior SARS-CoV-2 infection, vaccination status against COVID-19) were collected through a questionnaire and medical records for those hospitalized. A total of 913 patients were included in this study (813 adults ≥18 years old, 100 children
ISSN:2076-2607
2076-2607
DOI:10.3390/microorganisms12122573