Immediate effect of intravitreal injection of bevacizumab on intraocular pressure

To investigate the immediate effect of intravitreal injection of bevacizumab on intraocular pressure (IOP). This was a prospective and nonrandomized study. A total of 291 eyes with macular edema or active choroidal neovascularization were submitted to a single 1.25 mg (0.05 mL) bevacizumab intravitr...

Full description

Saved in:
Bibliographic Details
Published in:Clinical ophthalmology (Auckland, N.Z.) N.Z.), 2014-01, Vol.8 (default), p.1383-1388
Main Authors: Lemos-Reis, Ricardo, Moreira-Gonçalves, Nuno, Melo, António B, Carneiro, Angela M, Falcão-Reis, Fernando M
Format: Article
Language:English
Subjects:
Active control
Age
Bevacizumab
Cataracts
Control
Control equipment
Diabetes
Dosage and administration
Edema
Eyes
Glaucoma
Icare
Immunotherapy
Intraocular pressure
intravitreal injection
Macular degeneration
Monoclonal antibodies
Ophthalmology
Optic nerve
Original Research
Patients
Position measurement
Sex
Citations: Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:To investigate the immediate effect of intravitreal injection of bevacizumab on intraocular pressure (IOP). This was a prospective and nonrandomized study. A total of 291 eyes with macular edema or active choroidal neovascularization were submitted to a single 1.25 mg (0.05 mL) bevacizumab intravitreal injection. Intraocular pressure was measured with an Icare(®) tonometer immediately before and after injection in a seated position. The presence of subconjunctival reflux was recorded. The fellow eye served as the control. Mean preoperative IOP was 18.0±5.9 mmHg in the treated eye versus 16.9±6.0 mmHg in the fellow eye. Mean postoperative IOP was 42.1±14.5 mmHg in the treated eye versus 17.5±6.0 mmHg in the fellow eye. The IOP variation was statistically significant in both cases and controls (P
ISSN:1177-5467
1177-5483
1177-5483
DOI:10.2147/OPTH.S64721