Evaluation of the Antibacterial and Prebiotic Potential of Ascophyllum nodosum and Its Extracts Using Selected Bacterial Members of the Pig Gastrointestinal Microbiota

and its extracts are promising antibacterial and prebiotic dietary supplements for pigs. The objectives of this study were to evaluate the effects of the increasing concentrations of: (1) two whole biomass samples of with different harvest seasons, February (ANWB-F) and November (ANWB-N), in a weane...

Full description

Saved in:
Bibliographic Details
Published in:Marine drugs 2021-12, Vol.20 (1), p.41
Main Authors: Venardou, Brigkita, O'Doherty, John V, Garcia-Vaquero, Marco, Kiely, Claire, Rajauria, Gaurav, McDonnell, Mary J, Ryan, Marion T, Sweeney, Torres
Format: Article
Language:English
Subjects:
Algae
Animal Feed
Animals
Anti-Bacterial Agents - chemistry
Anti-Bacterial Agents - pharmacology
antibacterial
Antibiotics
Aquatic Organisms
Ascophyllum
Ascophyllum nodosum
Assaying
Bacteria
Bifidobacterium
Biomass
Dietary supplements
E coli
Ethanol
Fermentation
fucoidan
Gastrointestinal Microbiome - drug effects
Growth
Microbiological strains
Microbiota
Pathogens
Polyphenols
prebiotic
Prebiotics
Pure culture
Salmonella
seaweed polysaccharides
Swine
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:and its extracts are promising antibacterial and prebiotic dietary supplements for pigs. The objectives of this study were to evaluate the effects of the increasing concentrations of: (1) two whole biomass samples of with different harvest seasons, February (ANWB-F) and November (ANWB-N), in a weaned pig faecal batch fermentation assay, and (2) extracts produced using four different extraction conditions of a hydrothermal-assisted extraction methodology (ANE1-4) and conventional extraction methods with water (ANWE) and ethanol (ANEE) as solvent in individual pure culture growth assays using a panel of beneficial and pathogenic bacterial strains. In the batch fermentation assay, ANWB-F reduced spp. counts ( < 0.05) while ANWB-N increased total bacterial counts and reduced spp. and counts ( < 0.05). Of the ANE1-4, produced from ANWB-F, ANWE and ANEE that were evaluated in the pure culture growth assays, the most interesting extracts were the ANE1 that reduced Typhimurium, enterotoxigenic and counts and the ANE4 that stimulated growth ( < 0.05). In conclusion, the extraction method and conditions influenced the bioactivities of the extracts with ANE1 and ANE4 exhibiting distinct antibacterial and prebiotic properties in vitro, respectively, that merit further exploration.
ISSN:1660-3397
1660-3397
DOI:10.3390/md20010041