Prevalence of aortic aneurysms and dissections in patients with systemic vessel aneurysms and dissections; matched case-control study using a national sample cohort

• Published in: Frontiers in cardiovascular medicine 2023-10, Vol.10, p.1266430-1266430
• Main Authors: Song, Jihye, Lim, Yong Cheol, Kim, Do Jung
• Format: Article
• Language: English
• Subjects: aneurysm; aortic aneurysm; aortic disease; aortic dissection; Cardiovascular Medicine; peripheral artery disease
• ISSN: 2297-055X; 2297-055X
• DOI: 10.3389/fcvm.2023.1266430

ObjectiveAneurysms in systemic arteries are rare, and little is known about their relationship with aortic aneurysms. In this study, we aimed to evaluate the prevalence of aortic aneurysms and dissections (AAD) in patients with other systemic vessel aneurysms and dissections (OVAD) and identify their potential risk factors.MethodsThis cross-sectional study used a nationwide representative cohort sample from the Korea National Health Insurance Service-National Sample Cohort database. We defined OVAD as systemic vessel aneurysms and dissections excluding intracranial and aortic dissections and aneurysms. With a total of 690 OVAD patients and 2,760 non-OVAD matched controls, we investigated the prevalence of AAD in patients with OVAD and potential risk factors for their concurrence using the χ2 test and logistic regression.ResultsThe prevalence of AAD in patients with OVAD was 10.6% (73/690) and 0.3% (9/2,760) in patients with non-OVAD. The adjusted odds ratio (OR) for having concurrent AAD with OVAD was 37.56 (95% CI: 18.29-77.12, p