Molecular Identification of Fonsecaea monophora, Novel Agent of Fungal Brain Abscess

A 3-year-old patient in India experiencing headaches and seizures was diagnosed with a fungal infection, initially misidentified as Cladophialophora bantiana. Follow-up sequencing identified the isolate to be Fonsecaea monophora fungus. This case demonstrates the use of molecular methods for the cor...

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Bibliographic Details
Published in:Emerging infectious diseases 2024-06, Vol.30 (6), p.1232-1235
Main Authors: Gourav, Sudesh, Singh, Gagandeep, Pandey, Mragnayani, Rana, Bhaskar, Gupta, Sonakshi, Mishra, Himanshu, Xess, Immaculata
Format: Article
Language:English
Subjects:
Abscess
Abscesses
Antifungal Agents - pharmacology
Antifungal Agents - therapeutic use
Ascomycota - classification
Ascomycota - genetics
Ascomycota - isolation & purification
Biopsy
Brain
Brain Abscess - diagnosis
Brain Abscess - drug therapy
Brain Abscess - microbiology
Care and treatment
Case reports
Case studies
Child, Preschool
Diagnosis
disseminated phaeohyphomycosis
DNA, Fungal - genetics
Fonsecaea monophora
fungal brain abscess
Fungal infections
Fungi
Headache
Humans
Identification
India
Male
Mycoses
Mycoses - diagnosis
Mycoses - microbiology
Patients
Phylogenetics
Phylogeny
Potash
Potassium
Seizures (Medicine)
Citations: Items that this one cites
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Description
Summary:A 3-year-old patient in India experiencing headaches and seizures was diagnosed with a fungal infection, initially misidentified as Cladophialophora bantiana. Follow-up sequencing identified the isolate to be Fonsecaea monophora fungus. This case demonstrates the use of molecular methods for the correct identification of F. monophora, an agent of fungal brain abscess.
ISSN:1080-6040
1080-6059
1080-6059
DOI:10.3201/eid3006.240077