The impact of fresh gas flow on wash-in, wash-out time and gas consumption for sevoflurane and desflurane, comparing two anaesthesia machines, a test-lung study. [version 2; peer review: 3 approved]

Low-flow anaesthesia is considered beneficial for the patient and the environment, and it is cost reducing due to reduced anaesthetic gas consumption. An initial high-flow to saturate the circle system ( wash-in) is desirable from a clinical point of view. We measured the wash-in and wash-out times...

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Bibliographic Details
Published in:F1000 research 2017, Vol.6, p.1997
Main Authors: Leijonhufvud, Fredrik, Jöneby, Fredrik, Jakobsson, Jan G
Format: Article
Language:English
Subjects:
Algorithms
Alveoli
Anesthesia
Copyright
Critical care
Gas flow
Gases
Lungs
Medicin och hälsovetenskap
Research Note
Sevoflurane
Statistical analysis
Studies
Technology & Monitoring in Anesthesiology
Variance analysis
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Summary:Low-flow anaesthesia is considered beneficial for the patient and the environment, and it is cost reducing due to reduced anaesthetic gas consumption. An initial high-flow to saturate the circle system ( wash-in) is desirable from a clinical point of view. We measured the wash-in and wash-out times (time to saturate and to eliminate the anaesthetic agent, AA), for sevoflurane and desflurane, in a test-lung with fixed 3 MAC vaporizer setting at different fresh gas flow (FGF) and calculated the consumption of AA. We tried to find an optimal flow rate for speed and gas consumption, comparing two anaesthesia machines (AMs): Aisys and Flow-i. Time to reach 1 minimal alveolar concentration (MAC) (wash-in) decreased (p
ISSN:2046-1402
2046-1402
DOI:10.12688/f1000research.13064.2